Synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde and its transformation into amino alcohols containing an indan-1,3-dione fragment
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- Popov, L.D. & Suzdalev, K.F. Russ J Org Chem (2016) 52: 844. doi:10.1134/S1070428016060142
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A procedure for the synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde was developed and optimized. Its reaction with indan-1,3-dione, followed by treatment with amines, afforded 1,2-amino alcohols containing an indole fragment.