Russian Journal of General Chemistry

, Volume 81, Issue 1, pp 96–101

Synthesis and biological activity of the pinostrobin oxime complex compounds with some d-metals

  • A. A. Mashentseva
  • T. S. Seytembetov
  • S. M. Adekenov
  • B. I. Tuleuov
  • O. P. Loiko
  • A. I. Khalitova
Article

DOI: 10.1134/S1070363211010142

Cite this article as:
Mashentseva, A.A., Seytembetov, T.S., Adekenov, S.M. et al. Russ J Gen Chem (2011) 81: 96. doi:10.1134/S1070363211010142

Abstract

The process of the complex formation by the natural flavonoid pinostrobin (5-hydroxy-7-methoxyflavonone) oxime with the Cu(II) and Fe(III) ions in a water-ethanol medium was investigated. The metal: ligand ratio in the complex was determined by the saturation method. The results of the analysis of IR spectra and the data of mass-spectrometric studies of the structure of the obtained complex compounds are reported. The antiviral activity of the synthesized complexes with respect to the human immunodeficiency virus HIV-1 IIIB and HIV-2 ROD strains was studied. The antioxidant activity of the complexes, as well as the parent pinostrobin oxime ligand, was evaluated with respect to the diphenylpicrylhydrazyl (DPPH) radical and the 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical cation.

Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • A. A. Mashentseva
    • 1
  • T. S. Seytembetov
    • 1
  • S. M. Adekenov
    • 2
  • B. I. Tuleuov
    • 2
  • O. P. Loiko
    • 3
  • A. I. Khalitova
    • 3
  1. 1.Gumilev Eurasian National UniversityAstanaKazakhstan
  2. 2.International Holding “Phytochemistry,”KaragandaKazakhstan
  3. 3.Buketov Karaganda State UniversityKaragandaKazakhstan

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