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Shifts in metabolism and its regulation under the effect of spaceflight factors

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Abstract

The review discusses the results of studies on adaptive changes in metabolism and its neuroendocrine regulation in humans and animals exposed to spaceflight factors and ground-based simulation of gravitational unloading. The majority of investigations are related to the water–electrolyte and mineral metabolisms, as well as to the protein, lipid, and carbohydrate metabolisms. As a result, the investigations performed before, during and after spaceflights or in simulation experiments allowed researchers to evaluate the state of the sympathoadrenal, hypothalamo-pituitary-adrenal, and other systems responsible for the regulation of body metabolism and reflecting the expression level of responses to the body exposure to unfavorable factors of environment. The authors have generalized the obtained data on the interconnection and interference between the neuroendocrine and psychophysiological statuses in real and simulated spaceflight conditions.

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  1. Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia

    I. M. Larina, I. A. Nichiporuk, O. M. Veselova, G. Yu. Vasilieva & I. A. Popova

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  1. I. M. Larina
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Original Russian Text © I.M. Larina, I.A. Nichiporuk, O.M. Veselova, G.Yu. Vasilieva, I.A. Popova, 2013, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2013, Vol. 47, No. 1, pp. 21–30.

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Larina, I.M., Nichiporuk, I.A., Veselova, O.M. et al. Shifts in metabolism and its regulation under the effect of spaceflight factors. Hum Physiol 41, 689–698 (2015). https://doi.org/10.1134/S0362119715070105

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