Abstract
The dynamics of microtubule growth and disassembly is considered in the framework of the theory of nonequilibrium reaction-diffusion systems. The phase diagram contains regions corresponding to stable stationary and nonstationary solutions. Dynamic instabilities can arise from nonequilibrium kinetic transitions. Agents affecting the microtubule dynamics are classed into four types, and the interplay of their effects is analyzed.
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Original Russian Text © K.A. Katrukha, G.T. Guriya, 2006, published in Biofizika, 2006, Vol. 51, No. 5, pp. 885–893.
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Katrukha, K.A., Guriya, G.T. Dynamic instabilities in the microtubule cytoskeleton: A state diagram. BIOPHYSICS 51, 781–788 (2006). https://doi.org/10.1134/S0006350906050198
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DOI: https://doi.org/10.1134/S0006350906050198