, Volume 78, Issue 9, pp 1061-1070
Date: 15 Sep 2013

Studies that shed new light on aging

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Abstract

I will first discuss how all aging models that assume that the aged cell has irreversibly lost its youthful capabilities through such mechanisms as accumulated dysfunction, accumulated damage, and/or accumulation of toxic byproducts of metabolism have been shown to be incorrect. I will then briefly discuss models of aging and propose an experiment that would distinguish between those models and provide a basis for organismic rejuvenation.

Published in Russian in Biokhimiya, 2013, Vol. 78, No. 9, pp. 1354–1366.