Biochemistry (Moscow)

, Volume 78, Issue 9, pp 1061–1070

Studies that shed new light on aging

Phenoptosis

DOI: 10.1134/S0006297913090137

Cite this article as:
Katcher, H.L. Biochemistry Moscow (2013) 78: 1061. doi:10.1134/S0006297913090137

Abstract

I will first discuss how all aging models that assume that the aged cell has irreversibly lost its youthful capabilities through such mechanisms as accumulated dysfunction, accumulated damage, and/or accumulation of toxic byproducts of metabolism have been shown to be incorrect. I will then briefly discuss models of aging and propose an experiment that would distinguish between those models and provide a basis for organismic rejuvenation.

Key words

agingaging mechanismstheories of agingparabiosiscross-age transplantationrejuvenationcellular agingage-dependent transcriptional patterns

Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  1. 1.University of MarylandUniversity CollegeMarylandUSA