, Volume 78, Issue 6, pp 638-650
Date: 21 Jun 2013

New functions of small nucleolar RNAs

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Abstract

Small nucleolar RNAs (snoRNAs) are one of the most abundant and well-studied groups of non-coding RNAs. snoRNAs are mostly engaged in processing of rRNA. However, recent data indicate that snoRNAs are also involved in other processes including regulation of alternative splicing, translation and oxidative stress. snoRNAs are also involved in pathogenesis of some hereditary diseases and cancer. Therefore, the range of snoRNAs’ functions is significantly wider than it has been assumed earlier.

Original Russian Text © J. A. Makarova, S. M. Ivanova, A. G. Tonevitsky, A. I. Grigoriev, 2013, published in Biokhimiya, 2013, Vol. 78, No. 6, pp. 825–839.