Biochemistry (Moscow)

, Volume 78, Issue 6, pp 638–650

New functions of small nucleolar RNAs

Authors

    • Engelhardt Institute of Molecular BiologyRussian Academy of Sciences
    • Science and Technology Center Bioclinicum
  • S. M. Ivanova
    • Semashko Hospital at Lublino
  • A. G. Tonevitsky
    • Science and Technology Center Bioclinicum
    • Institute of General Pathology and PathophysiologyRussian Academy of Medical Sciences
    • Lomonosov Moscow State University
  • A. I. Grigoriev
    • State Research Center of the Russian Federation, Institute of Biomedical ProblemsRussian Academy of Sciences
Review

DOI: 10.1134/S0006297913060096

Cite this article as:
Makarova, J.A., Ivanova, S.M., Tonevitsky, A.G. et al. Biochemistry Moscow (2013) 78: 638. doi:10.1134/S0006297913060096

Abstract

Small nucleolar RNAs (snoRNAs) are one of the most abundant and well-studied groups of non-coding RNAs. snoRNAs are mostly engaged in processing of rRNA. However, recent data indicate that snoRNAs are also involved in other processes including regulation of alternative splicing, translation and oxidative stress. snoRNAs are also involved in pathogenesis of some hereditary diseases and cancer. Therefore, the range of snoRNAs’ functions is significantly wider than it has been assumed earlier.

Key words

snoRNAscaRNAsdRNAmiRNAnoncoding RNARNA silencingoncogenesis

Abbreviations

IRES

internal ribosome entry site

miRNAs

microRNAs

ncRNAs

noncoding RNAs

RNPs

ribonucleo-proteins

scaRNAs

small Cajal body-specific RNAs

sdRNAs

sno-derived RNAs

snoRNAs

small nucleolar RNAs

snRNAs

small nuclear RNAs

vRNAs

vault RNAs

Ψ

pseudouridine

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Copyright information

© Pleiades Publishing, Ltd. 2013