Biochemistry (Moscow)

, 76:1017

Telomerase activity in the bats Hipposideros armiger and Rousettus leschenaultia

Article

DOI: 10.1134/S0006297911090057

Cite this article as:
Wang, L., McAllan, B.M. & He, G. Biochemistry Moscow (2011) 76: 1017. doi:10.1134/S0006297911090057

Abstract

Telomerase activity was examined in two species of bat, Hipposideros armiger and Rousettus leschenaultia, which have similar body mass and lifespan but differ in use of hibernation. We found that telomerase activity was present in all tissues sampled, but it was greater in metabolically active tissues such as liver, spleen, and kidney. Of special interest is the raised activity found in the heterothermic bat H. armiger, and the hibernating bats having raised values for spleen, heart, and kidney. These findings show that maintenance of high levels of telomerase is an essential part of the regulation of cellular activities during hibernation.

Key words

bat body mass hibernation telomerase activity 

Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  1. 1.School of Life SciencesEast China Normal UniversityShanghaiChina
  2. 2.School of Medical Sciences, Discipline of Physiology, Anderson Stuart Building (F13)The University of SydneySydneyAustralia