, Volume 67, Issue 3, pp 493-511

Control of the medical treatment of AIDS

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This work deals with the statement and the solution of problems of optimal control of the human immune system affected by a human immunodeficiency virus (HIV). The solution is performed by the numerical methods of optimal control on the basis of a dynamic model of the development of an infection in the organism of a human being. The results illustrate the possibilities for the use of mathematical methods in the problem of extending the life of HIV-infected patients.

Original Russian Text © V.V. Velichenko, D.A. Pritykin, 2006, published in Avtomatika i Telemekhanika, 2006, No. 3, pp. 166–185.
This paper was recommended for publication by V.N. Novosel’tsev, a member of the Editorial Board