Applied Biochemistry and Microbiology

, Volume 48, Issue 5, pp 488–492

Aspergillus ochraceus micromycetes—producers of extracellular proteinases—protein C activators of blood plasma


    • Biological FacultyMoscow State University
  • V. G. Kreier
    • Biological FacultyMoscow State University
  • A. V. Kurakov
    • Biological FacultyMoscow State University
  • N. . Baranova
    • Biological FacultyMoscow State University
  • N. S. Egorov
    • International Biotechnological CenterMoscow State University

DOI: 10.1134/S0003683812050109

Cite this article as:
Osmolovskiy, A.A., Kreier, V.G., Kurakov, A.V. et al. Appl Biochem Microbiol (2012) 48: 488. doi:10.1134/S0003683812050109


Natural isolates of Aspergillus ochraceus micromycetes from soil and plant remains from various regions have been screened. The isolated strains were characterized by similar cultural and morphological features and an identical nucleotide sequence in the ITS1-5,8S-ITS2 region of rDNA. The ability of the extracellular proteinases of A. ochraceus micromycetes to activate protein C of blood plasma has been established. Differences are revealed in the accumulation of proteinases activating protein C and proteinases with thrombinand plasmin-like activities in the growth dynamics of producers.

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© Pleiades Publishing, Ltd. 2012