Annals of Biomedical Engineering

, Volume 30, Issue 10, pp 1251–1261

The Effect of Pulsed Ultrasound on Mandibular Distraction

Authors

  • Tarek H. El-Bialy
    • Tanta University, Egypt and Department of BioengineeringUniversity of Illinois at Chicago
  • Thomas J. Royston
    • Department of Mechanical EngineeringUniversity of Illinois at Chicago
  • Richard L. Magin
    • Department of BioengineeringUniversity of Illinois at Chicago
  • Carla A. Evans
    • Department of OrthodonticsUniversity of Illinois at Chicago
  • Abd El-Moneim Zaki
    • University of Illinois at Chicago
  • Leon A. Frizzell
    • Department of Electrical and Computer EngineeringUniversity of Illinois at Urbana-Champaign
Article

DOI: 10.1114/1.1529196

Cite this article as:
El-Bialy, T.H., Royston, T.J., Magin, R.L. et al. Annals of Biomedical Engineering (2002) 30: 1251. doi:10.1114/1.1529196

Abstract

This study evaluated the effect of pulsed ultrasound on tissue repair and bone growth during mandibular osteodistraction. Twenty-one rabbits were divided into three groups of 7. The distraction started 72 h after surgically severing both sides of the mandible and proceeded at a rate of 1.5 mm/12 h for 5 days. Group 1 received pulsed ultrasound (nominally 200 μs pulse of 1.5 MHz at a 1.1 kHz pulse repetition frequency, 30 mW/cm2) for 20 min on both sides of the mandible every other day (alternating sides). Group 2 received the same pulsed ultrasound treatment on one side of the mandible every day for 20 min. Group 3 did not receive any ultrasound treatment. Bone formation at the distraction site was assessed by photodensitometry on head radiographs, a vibratory coherence test across the distraction site, a postmortem three-point bending mechanical stiffness test, and a postmortem histological examination. Statistical analyses performed using analysis of variance revealed that pulsed ultrasound enhanced bone formation at the distraction site with a high level of significance when assessed by the increase in new bone photodensity (p=0.001), vibratory coherence (p=0.001), mechanical stiffness (p=0.003), and qualitative histological studies, especially when the pulsed ultrasound treatment was directly applied daily. © 2002 Biomedical Engineering Society.

PAC2002: 8750Kk, 8763Df

Bone healingBone formationDistraction osteogenesisTherapeutic pulsed ultrasound

Copyright information

© Biomedical Engineering Society 2002