The Cerebellum

, 6:280

Cognition in hereditary ataxia

Original Article

DOI: 10.1080/14734220601115924

Cite this article as:
Burk, K. Cerebellum (2007) 6: 280. doi:10.1080/14734220601115924


Apart from motor control the cerebellum has been implicated in higher cortical functions such as memory, fronto-executive functions, visuoconstructive skills and emotion. Clinical descriptions of hereditary ataxias mention cognitive impairment to a variable extent. Systematic neuropsychological studies are limited. Regarding the neuropathological pattern in different SCA types, cognitive deficits in hereditary ataxias are not likely to be contingent upon cerebellar degeneration but to result from disruption of cerebrocerebellar circuitries at various levels in the CNS.

Key words

Ataxiacognitive deficitsdominant genesrecessive genes

Copyright information

© Springer 2007

Authors and Affiliations

  1. 1.Department of NeurologyUniversity of MarburgGermany
  2. 2.Institute of Brain ResearchUniversity of TübingenTübingenGermany