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Association of HSV1 and apolipoprotein E-ε4 in Alzheimer’s disease

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References

  • Baringer JR, Pisani P (1994). Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction. Ann Neurol 36: 823–829.

    Article  CAS  PubMed  Google Scholar 

  • Bertrand P, Guillaume D, Hellauer K, Dea D, Lindsay J, Kogan S, Gauthier S, Poirier J (1993). Distribution of herpes simplex virus type 1 DNA in selected areas of normal and Alzheimer’s disease brains: a PCR study. Neurodegeneration 2: 201–208.

    Google Scholar 

  • Corder EH, Robertson K, Lannfelt L, Bogdanovic N, Eggertsen G, Wilkins J, Hall C (1998). HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nat Med 4: 1182–1184.

    Article  CAS  PubMed  Google Scholar 

  • Dobson CB, Itzhaki RF (1999). Herpes simplex virus type 1 and Alzheimer’s disease. Neurobiol Aging 20: 457–465.

    Article  CAS  PubMed  Google Scholar 

  • Gordon L, McQuaid S, Cosby SL (1996). Detection of herpes simplex virus (types 1 and 2) and human herpes virus 6 DNA in human brain tissue by polymerase chain reaction. Clin Diagn Virol 6: 33–40.

    Article  CAS  PubMed  Google Scholar 

  • Itzhaki RF, Lin W-R, Shang D, Wilcock GK, Faragher B, Jamieson GA (1997). Herpes simplex virus type 1 in brain and risk of Alzheimer’s disease. Lancet 349: 241–244.

    Article  CAS  PubMed  Google Scholar 

  • Jamieson GA, Maitland NJ, Wilcock GK, Craske J, Itzhaki RF (1991). Latent herpes simplex virus type 1 in normal and Alzheimer’s disease brains. J Med Virol 33: 224–227.

    Article  CAS  PubMed  Google Scholar 

  • Jamieson GA, Maitland NJ, Wilcock GK, Yates CM, Itzhaki RF (1992). Herpes simplex virus type 1 DNA is present in specific regions of brain from aged people with and without senile dementia of the Alzheimer type. J Pathol 167: 365–368.

    Article  CAS  PubMed  Google Scholar 

  • Lin W-R, Graham J, MacGowan SM, Wilcock GK, Itzhaki RF (1998). Alzheimer’s disease, herpes virus in brain, apolipoprotein E4 and herpes labialis. Alzheimer’s Repts 1: 173–178.

    Google Scholar 

  • Lin W-R, Wozniak MA, Esiri MM, Klenerman P, Itzhaki RF (2001). Herpes simplex encephalitis: involvement of apolipoprotein E genotype. J Neurol Neurosurg Psychiatry 70: 117–119.

    Article  CAS  PubMed  Google Scholar 

  • Marques AR, Straus SE, Fahle G, Weir Scako G, Fischer SH (2001). Lack of association between HSV-1 DNA in the brain, Alzheimer’s disease and apolipoprotein E4. J Neuro Virol 7: 82–83.

    CAS  Google Scholar 

  • Sanders VJ, Waddell AE, Felisan SL, Li X, Conrad AJ, Tourtellotte WW (1996). Herpes simplex virus in postmortem multiple sclerosis brain tissue. Arch Neurol 53: 125–133.

    CAS  PubMed  Google Scholar 

  • Wozniak MA, Lin, Cairns N, Mann DMA, Itzhaki RF In preparation.

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Authors and Affiliations

  1. Molecular Neurobiology Lab, Department of Optometry and Neuroscience, University of Manchester Institute of Science and Technology (UMIST), M60 1QD, Manchester, UK

    Ruth F. Itzhaki, Curtis B. Dobson, Woan-Ru Lin & Matthew A. Wozniak

Authors
  1. Ruth F. Itzhaki
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  2. Curtis B. Dobson
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  3. Woan-Ru Lin
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  4. Matthew A. Wozniak
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Correspondence to Ruth F. Itzhaki.

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Itzhaki, R.F., Dobson, C.B., Lin, WR. et al. Association of HSV1 and apolipoprotein E-ε4 in Alzheimer’s disease. Journal of NeuroVirology 7, 570–571 (2001). https://doi.org/10.1080/135502801753248169

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  • DOI: https://doi.org/10.1080/135502801753248169

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