Journal of Public Health Policy

, Volume 33, Issue 3, pp 368–381

Timing of hepatitis B vaccination and impact of non-simultaneous vaccination with DTP vaccine following introduction of a hepatitis B birth dose in the Philippines

Authors

    • Global Immunization Division, US Centers for Disease Control & Prevention
  • Howard Sobel
    • World Health Organization
  • Tove K Ryman
    • Global Immunization Division, US Centers for Disease Control & Prevention
  • Jacinto Blas Mantaring III
    • Department of Pediatrics, Manila Philippine General Hospital, University of the Philippines
  • Mianne Silvestre
    • Department of Pediatrics, Manila Philippine General Hospital, University of the Philippines
  • Margaret Thorley
    • Global Immunization Division, US Centers for Disease Control & Prevention
  • Joyce Ducusin
    • Department of Health, San Lazaro Hospital
  • Soe Nyunt-U
    • World Health Organization
Original Article

DOI: 10.1057/jphp.2012.18

Cite this article as:
S Wallace, A., Sobel, H., K Ryman, T. et al. J Public Health Pol (2012) 33: 368. doi:10.1057/jphp.2012.18

Abstract

Timely administration of hepatitis B vaccine beginning at birth prevents up to 95 per cent of perinatally acquired hepatitis B virus infections in infants of infected mothers. The Philippines changed its national HepB schedule in 2007 to include a dose at birth. We evaluated vaccination schedule change by reviewing infant records at selected health facilities to measure completeness and timeliness of HepB administration and frequency of recommended, simultaneous vaccination with diphtheria-tetanus-pertussis (DTP) vaccine. Of 1431 sampled infants, 1106 (77 per cent) completed the HepB series and 10 per cent followed the national schedule. The proportion with timely vaccination declined with successive doses: HepB1 (71 per cent), HepB2 (47 per cent), and HepB3 (26 per cent). Twenty-six per cent received HepB2 simultaneously with DTP1 and 34 per cent received HepB3 simultaneously with DTP3. If HepB and DTP vaccination were given simultaneously, 10 per cent more infants could have received all HepB doses. Program implementers should monitor vaccination timeliness and increase simultaneous administration to improve vaccination coverage and decrease disease incidence.

Keywords

hepatitis B birth dosevaccination timelinessimmunization schedule adherenceexpanded program on immunization

Copyright information

© Palgrave Macmillan, a division of Macmillan Publishers Ltd 2012