Journal of Mammary Gland Biology and Neoplasia

, Volume 2, Issue 3, pp 299–310

The Tammar Wallaby: A Model to Study Putative Autocrine-Induced Changes in Milk Composition

Authors

    • Division of Molecular Biology and GeneticsVictorian Institute of Animal Science
  • Kaylene Simpson
    • Division of Molecular Biology and GeneticsVictorian Institute of Animal Science
    • School of AgricultureLaTrobe University
  • Michael Wilson
    • Division of Molecular Biology and GeneticsVictorian Institute of Animal Science
    • Human Immunogenetics LaboratoryImperial Cancer Research Fund
  • Josephine Trott
    • Division of Molecular Biology and GeneticsVictorian Institute of Animal Science
    • Department of ZoologyMelbourne University
  • Denis Shaw
    • Protein Biochemistry GroupJohn Curtin School of Medical Research, Australian National University
Article

DOI: 10.1023/A:1026392623090

Cite this article as:
Nicholas, K., Simpson, K., Wilson, M. et al. J Mammary Gland Biol Neoplasia (1997) 2: 299. doi:10.1023/A:1026392623090

Abstract

The marsupial newborn is immature and the mother has the capacity to alter milk composition significantly during lactation, presumably to meet the nutritional requirements of the developing young. Furthermore, macropodid marsupials may practice asynchronous concurrent lactation (ACL)7whereby the mother provides milk which differs in all the major components from adjacent mammary glands for two young of different ages. This phenomenon suggests that local regulation of mammary function, in addition to endocrine stimuli, is likely to be important for controlling milk composition. This paper explores the possibility that changes in sucking patterns of the young represent the first step in a mechanism to signal the mammary gland for putative autocrine-induced changes in milk composition.

Marsupialmilk protein compositionasynchronous concurrent lactationsucking patternsautocrine regulationmilk protein genes
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Copyright information

© Plenum Publishing Corporation 1997