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Electrogastrographic Characteristics in Patients of Stomach Cancer

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Abstract

Using a homemade electrogastrography (EGG) system, we studied the characteristics of myoelectrical rhythm in gastric cancer (GC) patients. Based on a short-term Fourier transform, recorded slow waves could be automatically analyzed to obtain the following parameters: dominant frequency/power, percent of normal rhythm (2.4–3.7 cpm), power ratio, etc. Fifty histologically confirmed GC patients (34 men, 16 women) were enrolled before surgical intervention to measure their fasting and postprandial EGG parameters for 30 min. The cancerous parameters of GC patients were then obtained postoperatively. In addition, 46 healthy subjects were enrolled for comparison. When compared to controls, GC patients had the following characteristics: absence of postprandial increase in dominant frequency (GC: 3.04 ± 0.47 vs 3.07 ± 0.44 cpm, NS; controls: 3.02 ± 0.31 vs 3.21 ± 0.25 cpm, P < 0.001), marked power response after meal (P < 0.05), and obvious power ratio (4.58 ± 7.38 vs 2.27 ± 2.05, P < 0.05). Multivariate analysis indicated that advanced GC was the factor responsible for the obvious dominant power enhancement after meal (P < 0.05). Other demographic, clinical, and cancerous factors did not influence EGG parameters. We conclude that apparent arrhythmia is not encountered in GC patients, although they mainly exhibit obvious postprandial power response. Advanced GC is likely responsible for this power enhancement on EGG recording.

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Authors and Affiliations

  1. Division of Gastroenterology, Taipei Veterans General Hospital and School of Medicine National Yang Ming University, Taiwan

    Full-Young Chang, Ching-Liang Lu, Chih-Yen Chen & Shou-Dong Lee

  2. Division of General Surgery, Taipei Veterans General Hospital and School of Medicine National Yang Ming University, Taiwan

    Chew-Wun Wu

  3. Institute of Biomedical Engineering, National Yang Ming University, Taiwan

    Shuenn-Tsong Young

  4. Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan

    Han Chang Wu & Te-Son Kuo

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  1. Full-Young Chang
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Chang, FY., Lu, CL., Chen, CY. et al. Electrogastrographic Characteristics in Patients of Stomach Cancer. Dig Dis Sci 46, 1458–1465 (2001). https://doi.org/10.1023/A:1010687804141

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