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Use of alkaline proteases for ultrafiltration membrane cleaning

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Biotechnology Techniques

Abstract

Ability of alkaline proteases to clean ultrafiltration membranes fouled during milk processing was determined in two alkaline UF membrane cleaner, Alconox and Ultrasil. Optimum hydrolysis of milk proteins was observed with 5 g enzyme/l and showed a linear increase in water flux from 37.6 l m−2 h to 212.4 l m−2 h after 0.67 h. Enzyme performance was synergistically enhanced in combination with Alconox cleaner and exhibited 100% flux restoration.

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References

  • Cheryan M (1986). Ultrafiltration Handbook, Lancaster: Technomic Publishing Co.

    Google Scholar 

  • Hagihara B, Matsubara H, Nakai M, Okunuki K (1958) J. Biochem. 45: 185-194.

    Google Scholar 

  • Henz MH, Glatz CE (1991) J. Dairy Sci. 74: 11-19.

    Google Scholar 

  • Kumar CG (1997) Studies on microbial alkaline proteases for use in dairy detergents. Ph.D. Thesis, National Dairy Research Institute (Deemed University), Karnal, India.

    Google Scholar 

  • Kumar CG, Takagi H (1998) Biotechnol. Adv. (in Press).

  • Kumar CG, Malik RK, Tiwari MP, Jany KD (1997) Proceedings of 8th European Congress on Biotechnology, August 17–21, Budapest, Hungary, p. 37.

  • Kumar CG, Prasad DN, Tiwari MP (1998) Indian Dairyman 50: 15-19.

    Google Scholar 

  • Lee DN, Merson RL (1976) J. Food Sci. 41: 778-786.

    Google Scholar 

  • Parkin MF, Marshall KR (1976) New Zealand J. Dairy Sci. Technol. 11: 107-113.

    Google Scholar 

  • Renner E, El-Salam A (eds) (1991) Applications of Ultrafiltration in the Dairy Industry, London: Elsevier.

    Google Scholar 

  • Smith KE, Bradley RL, Jr (1987) J. Dairy Sci. 70: 243-251.

    Google Scholar 

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Kumar, C.G., Tiwari, M. Use of alkaline proteases for ultrafiltration membrane cleaning. Biotechnology Techniques 13, 235–238 (1999). https://doi.org/10.1023/A:1008990327859

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  • DOI: https://doi.org/10.1023/A:1008990327859

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