Digestive Diseases and Sciences

, Volume 45, Issue 5, pp 982–986

Prediction of Short-Term Outcome for Patients with Active Ulcerative Colitis

Authors

  • Nobuhide Oshitani
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Takayuki Matsumoto
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Yoshio Jinno
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Yoshinori Sawa
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Junichi Hara
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Shiro Nakamura
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Tetsuo Arakawa
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Atsuo Kitano
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
  • Tetsuo Kuroki
    • Third Department of Internal MedicineOsaka City University Medical School
    • Osaka Municipal Sumiyoshi Shimin Hospital
Article

DOI: 10.1023/A:1005589428082

Cite this article as:
Oshitani, N., Matsumoto, T., Jinno, Y. et al. Dig Dis Sci (2000) 45: 982. doi:10.1023/A:1005589428082

Abstract

We report results of a retrospective chart review to evaluate factors predicting short-term outcome of patients with ulcerative colitis treated by corticosteroids. Between January 1992 and December 1997, we treated 71 patients with ulcerative colitis (44 with severe and 27 with moderately severe disease). Forty-nine patients were treated by conventional prednisolone therapy and 22 patients by steroid pulse therapy. There were no differences in clinical or endoscopic improvement between the two treatments. Clinical examination showed that 41 patients entered remission, 17 patients improved, and 13 patients did not respond. Endoscopically, 26 patients entered remission, 30 patients improved, and 15 patients did not respond. Extent of disease, type of disease (first attack, relapsing, or chronic active type), and endoscopic findings were factors useful in predicting short-term outcome of medical treatment.

ulcerative colitisprognosispredictioncorticosteroidoutcome

Copyright information

© Plenum Publishing Corporation 2000