Somatic Cell and Molecular Genetics

, Volume 25, Issue 1, pp 33–39

The Human RNA Helicase A (DDX9) Gene Maps to the Prostate Cancer Susceptibility Locus at Chromosome Band 1q25 and Its Pseudogene (DDX9P) to 13q22, Respectively

  • Chee-Gun Lee
  • Toshihiko Eki
  • Katsuzumi Okumura
  • Masahiro Nogami
  • Vera da Costa Soares
  • Yasufumi Murakami
  • Fumio Hanaoka
  • Jerard Hurwitz
Article

DOI: 10.1023/B:SCAM.0000007138.44216.3a

Cite this article as:
Lee, CG., Eki, T., Okumura, K. et al. Somat Cell Mol Genet (1999) 25: 33. doi:10.1023/B:SCAM.0000007138.44216.3a

Abstract

RNA helicase A is the homolog of the Drosophila maleless protein, an essential factor involved in dosage compensation, and plays a crucial role in early development in mammals. Here, we have mapped the human RNA helicase A (DDX9) gene to the major susceptibility locus for prostate cancer at chromosome band 1q25, and its pseudogene (DDX9P) to the band 13q22 by fluorescence in situ hybridization, somatic cell hybrid analysis, and assignment of YAC clones, respectively.

Copyright information

© Plenum Publishing Corporation 1999

Authors and Affiliations

  • Chee-Gun Lee
    • 1
  • Toshihiko Eki
    • 2
  • Katsuzumi Okumura
    • 3
  • Masahiro Nogami
    • 3
  • Vera da Costa Soares
    • 1
  • Yasufumi Murakami
    • 2
  • Fumio Hanaoka
    • 2
  • Jerard Hurwitz
    • 1
  1. 1.Graduate Program in Molecular BiologyMemorial Sloan-Kettering Cancer CenterNew York
  2. 2.Cellular Physiology LaboratoryThe Institute of Physical and Chemical Research (RIKEN)SaitamaJapan
  3. 3.Faculty of BioresourcesMie University, TsuMieJapan
  4. 4.Department of Biochemistry and Molecular BiologyUMDNJ-New Jersey Medical SchoolNewark
  5. 5.Department of Biological Science and Technology, Faculty of Industrial Science and TechnologyScience University of Tokyo, NodaChibaJapan