Elucidation of Structure of Lipid A from the Marine Gram-Negative Bacterium Pseudoalteromonas haloplanktis ATCC 14393T
- Cite this article as:
- Krasikova, I.N., Kapustina, N.V., Isakov, V.V. et al. Russian Journal of Bioorganic Chemistry (2004) 30: 367. doi:10.1023/B:RUBI.0000037264.53294.da
The chemical structure of lipid A, from the marine γ-proteobacterium Pseudoalteromonashaloplanktis АТСС 14393Т, a main product of lipopolysaccharide hydrolysis (1% AcOH), was determined using chemical methods and NMR spectroscopy. The lipid A was shown to be β-1,6-glucosaminobiose 1,4′-diphosphate acylated with two (R)-3-hydroxyalkanoic acid residues at C3 and C3′ and amidated with one (R)-3-hydroxydodecanoyl and one (R)-3-dodecanoyloxydodecanoyl residue at N2 and N2′, respectively.