Metal-Enhanced Fluorescence Solution-Based Sensing Platform
- Cite this article as:
- Aslan, K., Lakowicz, J.R., Szmacinski, H. et al. Journal of Fluorescence (2004) 14: 677. doi:10.1023/B:JOFL.0000047217.74943.5c
In recent years our laboratories have reported the favorable effects for fluorophores placed in close proximity to surface immobilized silver nanostructures. These include; greater quantum yields, reduced lifetimes (increased photostability) and directional emission. However, while these findings are likely to find multifarious applications for surface assays based on enhanced fluorescence detection, a solution based enhanced sensing platform has yet to be realized. In this short, note, we show how SiO2-coated silver colloids, indeed provide for a solution based enhanced fluorescence sensing platform with a 3–5 fold enhancement typically observed.