Journal of Bioenergetics and Biomembranes

, Volume 36, Issue 1, pp 107-113

First online:

Rieske Iron–Sulfur Proteins from Extremophilic Organisms

  • C. L. SchmidtAffiliated withInstitut für Biochemie der Universität Lübeck

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


Proteins located on the outside of the membranes of organisms thriving under extreme conditions like high or low pH, or high salinity face special challenges maintaining their structural integrity. This review is focused on the Rieske iron–sulfur proteins from these organisms. Rieske proteins are essential subunits of the cytochrome bc-complexes, which are often of crucial importance for the energy metabolism of the cells. On the basis of the available data we propose strategies by which these proteins are able to stabilize their noncovalent bound cofactor and adapt to the function under extreme conditions.

Rieske protein iron–sulfur cluster stability redox potential structure