, Volume 59, Issue 10, pp 1002-1005

The 125th Anniversary of the Griess Reagent

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The creation of the Griess reagent for nitrites is an example of the first directed synthesis of an organic reagent in analytical chemistry. In connection with the jubilee of the reagent, some aspects of the use of diazotization and azo coupling reactions for determining nitrites and nitrates are considered. It is shown that the Griess reaction is widely used at present; however, the components of this reaction and the methods for determining nitrites are continuously improved.