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Effects of an Oral Vitamin B12 Formulation on AIDS-Related Neuropathy and Other Symptoms: A Pilot Study

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Journal of Advancement in Medicine

Abstract

In a preliminary uncontrolled trial, an oral vitamin B12 formulation (cyanocobalamin aminolate, trade name CobamaxTM) containing 600 μg vitamin B12 per day was administered to a small cohort of HIV + individuals, most of whom had been previously diagnosed with AIDS. Responses to a set of self-rated questionnaires suggested that the vitamin formulation was remarkably effective in moderating or resolving a broad range of AIDS-related symptoms, including fatigue, depression, night sweats, oral thrush, fevers, diminished appetite, gastrointestinal distress, impaired memory and concentration, pain in general and peripheral neuropathy. These preliminary results remain to be confirmed by additional studies.

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Authors and Affiliations

  1. Department of Chemistry, Bronx Community College, The Bronx, New York and Argos Biologicals, Ltd., Nyack, New York

    Thomas F. Brennan

  2. Argos Biologicals, Ltd., Nyack, New York

    William J. Sarill

  3. Health Force, The Bronx, New York

    Chris Norwood

Authors
  1. Thomas F. Brennan
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  2. William J. Sarill
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  3. Chris Norwood
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Correspondence to Thomas F. Brennan.

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Brennan, T.F., Sarill, W.J. & Norwood, C. Effects of an Oral Vitamin B12 Formulation on AIDS-Related Neuropathy and Other Symptoms: A Pilot Study . Journal of Advancement in Medicine 12, 97–117 (1999). https://doi.org/10.1023/B:JAME.0000008702.16484.70

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  • DOI: https://doi.org/10.1023/B:JAME.0000008702.16484.70

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