Article

Journal of Autism and Developmental Disorders

, Volume 34, Issue 2, pp 129-137

First online:

Interrelationship Between Autism Diagnostic Observation Schedule-Generic (ADOS-G), Autism Diagnostic Interview-Revised (ADI-R), and the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) Classification in Children and Adolescents with Mental Retardation

  • Annelies de BildtAffiliated withChild and Adolescent Psychiatry, University of Groningen
  • , Sjoerd SytemaAffiliated withChild and Adolescent Psychiatry, University of Groningen
  • , Cees KetelaarsAffiliated withChild and Adolescent Psychiatry, University of Groningen
  • , Dirk KraijerAffiliated withStichting Hendrik van Boeijen
  • , Erik MulderAffiliated withChild and Adolescent Psychiatry, University of Groningen
  • , Fred VolkmarAffiliated withChild Study Center, Yale University
  • , Ruud MinderaaAffiliated withChild and Adolescent Psychiatry, University of Groningen

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Abstract

The interrelationship between the Autism Diagnostic Interview-Revised (ADI-R), Autism Diagnostic Observation Schedule-Generic (ADOS-G) and clinical classification was studied in 184 children and adolescents with Mental Retardation (MR). The agreement between the ADI-R and ADOS-G was fair, with a substantial difference between younger and older children (5–8 vs. 8+ years). Compared with the Diagnostic and Statistical Manual of Mental Disorders-IV-TR (DSM-IV-TR) classification of Autistic Disorder (AD) and Pervasive Developmental Disorder (PDD), both instruments measure AD or PDD validly and reliably. Even in low-functioning children the interrelationship between the instruments and the clinical classification was satisfactory. The combination of ADI-R and ADOS-G identifies AD or PDD, as described in the DSM-IV-TR, most appropriately. Both instruments seem to be of great value in the diagnostic process of PDD in children and adolescents with MR.

ADI-R ADOS-G PDD MR