Feldmann, M., R. N. Maini, J. Bondeson, P. Taylor, B. M. Foxwell, and F. M. Brennan. 2001. Cytokine blockade in rheumatoid arthritis. Adv. Exp. Med. Biol.
Targan, S. R. 2000. Biology of inflammation in Crohn's disease: Mechanisms of action of anti-TNF-α therapy. Can. J. Gastroenterol.
14(Suppl. C): 13C-16C.
Bondeson, J. and R. N. Maini. 2001. Tumour necrosis factor as a therapeutic target in rheumatoid arthritis and other chronic inflammatory diseases: The clinical experience with infliximab (REMICADE). Int. J. Clin. Pract.
Libby, P. and Z. S. Galis. 1995. Cytokines regulate genes involved in atherogenesis. Ann. N. Y. Acad. Sci.
Sullivan, G. W., I. J. Sarembock, and J. Linden. 2000. The role of inflammation in vascular diseases. J. Leukoc. Biol.
Rose, D. M., B. W. Winston, E. D. Chan, D. W. Riches, and P. M. Henson. 1997. Interferon-gamma and transforming growth factor-beta modulate the activation of mitogen-activated protein kinases and tumor necrosis factor-alpha production induced by Fc gamma-receptor stimulation in murine macrophages. Biochem. Biophys. Res. Commun.
Hayes, M. P., S. L. Freeman, and R. P. Donnelly. 1995. IFN-gamma priming of monocytes enhances LPS-induced TNF production by augmenting both transcription and MRNA stability. Cytokine
Sweet, M. J. and D. A. Hume. 1996. Endotoxin signal transduction in macrophages. J. Leukoc. Biol.
Guha, M. and N. Mackman. 2001. LPS induction of gene expression in human monocytes. Cell Signal.
Foreback, J. L., V. Sarma, N. R. Yeager, E. M. Younkin, D. G. Remick, and P. A. Ward. 1998. Blood mononuclear cell production of TNF-α and IL-8: Engagement of different signal transduction pathways including the p42 MAP kinase pathway. J. Leukoc. Biol.
Rose, D. M., B. W. Winston, E. D. Chan, D. W. Riches, P. Gerwins, G. L. Johnson, and P. M. Henson. 1997. Fc gamma receptor cross-linking activates p42, p38, and JNK/SAPK mitogen-activated protein kinases in murine macrophages: Role for p42MAPK in Fc gamma receptor-stimulated TNF-alpha synthesis. J. Immunol.
Sanchez-Mejorada, G. and C. Rosales. 1998. Fcgamma receptor-mediated mitogen-activated protein kinase activation in monocytes is independent of Ras. J. Biol. Chem.
Scholl, P. R., D. Ahern, and R. S. Geha. 1992. Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line THP-1. J. Immunol.
Trotta, R., P. Kanakaraj, and B. Perussia. 1996. Fc gamma R-dependent mitogen-activated protein kinase activation in leukocytes: A common signal transduction event necessary for expression of TNF-alpha and early activation genes. J. Exp. Med.
Kobayashi, T. and H. Seguchi. 1999. Novel insight into current models of NADPH oxidase regulation, assembly and localization in human polymorphonuclear leukocytes. Histol. Histopathol.
Babior, B. M. 1999. NADPH oxidase: An update. Blood
Huang, Y., A. Jaffa, S. Koskinen, A. Takei, and M. F. Lopes-Virella. 1999. Oxidized LDL-containing immune complexes induce Fc gamma receptor I-mediated mitogen-activated protein kinase activation in THP-1 macrophages. Arterioscler. Thromb. Vasc. Biol.
Li, Q., V. Subbulakshmi, A. P. Fields, N. R. Murray, and M. K. Cathcart. 1999. Protein kinase calpha regulates human monocyte O-2 production and low density lipoprotein lipid oxidation. J. Biol. Chem.
Sanchez-Mejorada, G. and C. Rosales. 1998. Signal transduction by immunoglobulin Fc receptors. J. Leukoc. Biol.
Lennartz, M. R. 1999. Phospholipases and phagocytosis: The role of phospholipid-derived second messengers in phagocytosis. Int. J. Biochem. Cell Biol.
Larsen, E. C., J. A. Digennaro, N. Saito, S. Mehta, D. J. Loegering, J. E. Mazurkiewicz, and M. R. Lennartz. 2000. Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells. J. Immunol.
Cox, D., P. Chang, Q. Zhang, P. G. Reddy, G. M. Bokoch, and S. Greenberg. 1997. Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes. J. Exp. Med.
Refici, M. L., D. W. Metzger, B. P. Arulanandam, M. R. Lennartz, and D. J. Loegering. 2001. Fc gamma-receptor signaling augments the LPS-stimulated increase in serum tumor necrosis factor-α levels. Am. J. Physiol. Regul. Integr. Comp. Physiol.
Schultz, H., K. Engel, and M. Gaestel. 1997. PMA-induced activation of the p42/44ERK-and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentation to the macrophage-like phenotype. J. Cell Physiol.
Chen, C. C. and J. K. Wang. 1999. p38 but not p44/42 mitogen-activated protein kinase is required for nitric oxide synthase induction mediated by lipopolysaccharide in RAW 264.7 macrophages. Mol. Pharmacol.
Karimi, K. and M. R. Lennartz. 1998. Mitogen-activated protein kinase is activated during IgG-mediated phagocytosis, but is not required for target ingestion. Inflammation
Boehm, U., T. Klamp, M. Groot, and J. C. Howard. 1997. Cellular responses to interferon-gamma. Annu. Rev. Immunol.
Zheng, L., T. P. Zomerdijk, C. Aarnoudse, R. Van Furth, and P. H. Nibbering. 1995. Role of protein kinase C isozymes in Fc gamma receptor-mediated intracellular killing of Staphylococcus aureus by human monocytes. J. Immunol.
Dasgupta, D., P. Chakraborty, and M. K. Basu. 2000. Ligation of Fc receptor of macrophages stimulates protein kinase C and anti-leishmanial activity. Mol. Cell Biochem.
Ahn, S. K., Y. K. Shin, H. J. Kang, E. S. Han, and C. S. Lee. 1996. Effects of protein kinase inhibitors on the stimulated neutrophil responses by degraded immunoglobulin G. Eur. J. Pharmacol.
Karimi, K. and M. R. Lennartz. 1995. Protein kinase C activation precedes arachidonic acid release during IgG-mediated phagocytosis. J. Immunol.
Yamamoto, H., K. Hanada, and M. Nishijima. 1997. Involvement of diacylglycerol production in activation of nuclear factor kappaB by a CD14-mediated lipopolysaccharide stimulus. Biochem. J.
325 (Pt 1):223-228.
West, M. A., L. Clair, and J. Bellingham. 1996. Role of calcium in lipopolysaccharide-stimulated tumor necrosis factor and interleukin-1 signal transduction in naive and endotoxin-tolerant murine macrophages. J. Trauma
Natarajan, V. and G. K. Iwamoto. 1994. Lipopolysaccharide-mediated signal transduction through phospholipase D activation in monocytic cell lines. Biochim. Biophys. Acta
Procyk, K. J., P. Kovarik, A. Von Gabain, and M. Baccarini. 1999. Salmonella typhimurium and lipopolysaccharide stimulate extracellularly regulated kinase activation in macrophages by a mechanism involving phosphatidylinositol 3-kinase and phospholipase D as novel intermediates. Infect. Immun.
Zheng, L., P. H. Nibbering, and R. Van Furth. 1993. Stimulation of the intracellular killing of Staphylococcus aureus by human monocytes mediated by Fc gamma receptors I and II. Eur. J. Immunol.
Melendez, A. J., L. Bruetschy, R. A. Floto, M. M. Harnett, and J. M. Allen. 2001. Functional coupling of Fc gamma RI to nicotinamide adenine dinucleotide phosphate (reduced form) oxidative burst and immune complex trafficking requires the activation of phospholipase D1. Blood.
Watson, F. and S. W. Edwards. 1998. Stimulation of primed neutrophils by soluble immune complexes: Priming leads to enhanced intracellular Ca2+ elevations, activation of phospholipase D, and activation of the NADPH oxidase. Biochem. Biophys. Res. Commun.
Garcia-Garcia, E., G. Sanchez-Mejorada, and C. Rosales. 2001. Phosphatidylinositol 3-kinase and ERK are required for NF-kappaB activation but not for phagocytosis. J. Leukoc. Biol.
Yamamori, T., O. Inanami, H. Nagahata, Y. Cui, and M. Kuwabara. 2000. Roles of p38 MAPK, PKC and PI3-K in the signaling pathways of NADPH oxidase activation and phagocytosis in bovine polymorphonuclear leukocytes. FEBS Lett.