, Volume 120, Issue 1, pp 79-86

First online:

Molecular Polymorphism in Drosophila Melanogaster and D. Simulans: what have we Learned from Recent Studies?

  • Sylvain MoussetAffiliated withLaboratoire d’Ecologie, Université Paris VI, CNRS UMR 7625Laboratoire Biologie Intégrative des Populations, École Pratique des Hautes ÉtudesDept. Biology II, Ludwig-Maximilians-University
  • , Nicolas DeromeAffiliated withLaboratoire Populations, Génétique et Evolution, CNRS UPR 9034Laboratoire Biologie Intégrative des Populations, École Pratique des Hautes Études

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We present a review of recent studies of molecular polymorphism in Drosophila melanogaster and D. simulans. The availability of African and non-African samples for these species makes it possible to compare microsatellite and DNA sequence polymorphism between these species, both inside and outside their native regions. There are four main results: (i) variability is larger in African populations; (ii) variation is usually higher on the autosomes, except for African D. melanogaster; (iii) DNA sequence variation is higher on D. simulans than on D. melanogaster autosomes; (iv) the ratio of replacement to silent polymorphisms is higher for D. melanogaster autosomal loci. We summarize the main hypotheses put forward to explain these results.

Africa DNA sequence polymorphism Drosophila melanogaster Drosophila simulans microsatellite variation population genetics