Molecular Polymorphism in Drosophila Melanogaster and D. Simulans: what have we Learned from Recent Studies?
- Cite this article as:
- Mousset, S. & Derome, N. Genetica (2004) 120: 79. doi:10.1023/B:GENE.0000017632.08718.df
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We present a review of recent studies of molecular polymorphism in Drosophila melanogaster and D. simulans. The availability of African and non-African samples for these species makes it possible to compare microsatellite and DNA sequence polymorphism between these species, both inside and outside their native regions. There are four main results: (i) variability is larger in African populations; (ii) variation is usually higher on the autosomes, except for African D. melanogaster; (iii) DNA sequence variation is higher on D. simulans than on D. melanogaster autosomes; (iv) the ratio of replacement to silent polymorphisms is higher for D. melanogaster autosomal loci. We summarize the main hypotheses put forward to explain these results.