Cell and Tissue Banking

, Volume 4, Issue 2, pp 147–150

Use of Irradiated Amnion as a Biological Dressing in the Treatment of Radiation Induced Ulcers

Article

DOI: 10.1023/B:CATB.0000007024.81019.03

Cite this article as:
Lobo Gajiwala, A. & Sharma, V. Cell Tissue Banking (2003) 4: 147. doi:10.1023/B:CATB.0000007024.81019.03

Abstract

The management of moist skin desquamation (ulceration) following radiation therapy has been a concern since the inception of this therapy. The treatment of skin reactions focuses on promoting healing, improving patient comfort preventing infection and decreasing trauma to the area. Various dressings like topical preparations, hydrocolloid and gentian violet 1 % dressing have been used for its treatment. We present our experience with the use of amnion as a biological dressing in patients with radiation induced ulceration following pelvic radiation using megavoltage beam. The preliminary experience with treatment in 14 patients proved to be cost effective due to a shorter duration of ulcer healing (median of 7 days), fewer dressing changes (median of 4 dressings) and diminished use of analgesics.

amnionbiological dressingpost radiation ulceration

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  1. 1.Tissue BankTata Memorial HospitalParel, MumbaiIndia
  2. 2.Department of Radiation OncologyTata Memorial HospitalParel, MumbaiIndia