Population-Based Statistics for Women Diagnosed with Inflammatory Breast Cancer (United States)
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Objective: The purpose of this study was to use population-based information to describe the demographic and tumor characteristics of inflammatory breast cancer (IBC)– the most aggressive form of this disease.
Methods: IBC cases diagnosed during 1994 through 1998 were reported to 26 population-based cancer registries covering approximately 40% of the US population. Rates were expressed per 100,000 female population and age-adjusted to the 2000 US population. Ninety-five percent gamma confidence limits were estimated for the rates.
Results: Among the 3626 women diagnosed with IBC during 1994–1998, the majority were 40–59 years old. Most tumors were diagnosed at a regional (68.9%) or distant (25.3%) stage and were poorly differentiated (49.4%). The rate of IBC was 1.3 per 100,000 for all races combined. Black women had the highest risk (1.6) and Asian and Pacific Islander women the lowest (0.7).
Conclusions: IBC is an extremely rare form of breast cancer. More precise diagnostic criteria are needed to distinguish it from less aggressive forms of the disease. Future studies should use a population-based design and collect detailed clinical information, including the presence of erythema, edema or peau d'orange appearance of the skin, and other clinical signs of disease.
- Levine, PH, Steinhorn, SC, Ries, LG, Aron, JL (1985) Inflammatory breast cancer: the experience of the surveillance, epidemiology, and end results (SEER) program. J Natl Cancer Inst 74: pp. 291-297
- Margoles, RG, Fisher, B, Hortobagyi, H, Bloomer, WG Neoplasms of the breast. In: Bast, RC, Kufe, DW, Pollock, RE, Weichselbaum, RR, Holland, JF, Frei, E eds. (2000) Cancer Medicine. B.C. Decker Inc., Hamilton, Ontario
- Jaiyesimi, IA, Buzdar, AU, Hortobagyi, G (1992) Inflammatory breast cancer: a review. J Clin Oncol 10: pp. 1014-1024
- Chang, S, Parker, SL, Pham, T, Buzdar, AU, Hursting, SD (1998) Inflammatory breast carcinoma incidence and survival, the surveillance, epidemiology, and end results program of the National Cancer Institute, 1975-1992. Cancer 82: pp. 2366-2372
- Taylor, G, Meltzer, A (1938) Inflammatory carcinoma of the breast. Am J Cancer 33: pp. 33-49
- Haagensen, C (1971) Diseases of the Breast. Saunders, Philadelphia, PA
- Singletary, SE, Ames, FC, Buzdar, AU (1994) Management of inflammatory breast cancer. World J Surg 18: pp. 87-92
- Bonnier, P, Charpin, C, Lejeune, C (1995) Inflammatory carcinomas of the breast: a clinical pathological, or a clinical and pathological definition?. Int J Cancer 62: pp. 382-385
- Dahlbeck, SW, Donnelly, JF, Theriault, RL (1995) Differentiating inflammatory breast cancer from acute mastitis. Am Fam Physician 52: pp. 929-934
- Brooks, HL, Mandava, N, Pizzi, W, Shah, S (1998) Inflammatory breast carcinoma: a community hospital experience. Am College Surgeons 186: pp. 622-629
- Percy, C, Van Holten, V, Muir, C eds. (1990) International Classification of Diseases for Oncology. World Health Organization, Geneva, Switzerland
- Chang, S, Buzdar, AU, Hursting, SD (1998) Inflammatory breast cancer and body mass index. J Clin Oncol 16: pp. 3731-3735
- SEER*Stat 2001(2003) Bethesda, MD: National Cancer Institute. Also available from: URL: http://seer.cancer.gov/seerstat [accessed 2003, January 13].
- Fay, MP, Feuer, EJ (1997) Confidence intervals for directly standardized rates: a method based on the gamma distribution. Statist Med 16: pp. 791-801
- Ries, LAG, Eisner, MP, Kosary, CL eds. (2002) SEER Cancer Statistics Review, 1973-1999. National Cancer Institute, Bethesda, MD
- Katz, D, Baptista, J, Azen, SP, Pike, MC (1978) Obtaining confidence intervals for the risk ratio in cohort studies. Biometrics 34: pp. 469-474
- O'Malley C, Hu KU, West DW (2002) North American association of central cancer registries: race and ethnicity identifier assessment project. Also available from: URL http://www.naaccr.org, http://www.naaccr.org/Training/files [accessed August 2002].
- Ries, LAG, Eisner, MP, Kosary, CL eds. (2001) SEER Cancer Statistics Review, 1973-1998. National Cancer Institute, Bethesda, MD
- Greene, FL, Page, DL, Fleming, ID eds. (2002) AJCC Cancer Staging Manual. Springer-Verlag, New York
- United States Cancer Statistics: 1999 Incidence. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute, Atlanta, GA
- Rosenberg HM, Maurer JD, Sorlie PD, et al.(1999) Quality of death rates by race and Hispanic origin: a summary of current research. Vital Health Stat 2(128).
- Poe, GS, Powell-Griner, E, McLaughlin, JK, Placek, PJ, Thompson, GB, Robinson, K (1993) Comparability of the Death Certificate and the 1986 National Mortality Followback Survey. National Center for Health Statistics, Hyattsville, MD
- Kolonel, LH, Goodman, MT (1992) Racial variation in cancer: fact or artifact?. J Natl Cancer Inst 84: pp. 916-917
- Hogan, H (1993) The 1990 post-enumeration survey: operations and results. J Am Stat Assoc 88: pp. 1047-1060
- Population-Based Statistics for Women Diagnosed with Inflammatory Breast Cancer (United States)
Cancer Causes & Control
Volume 15, Issue 3 , pp 321-328
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- Kluwer Academic Publishers
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- breast cancer
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- Author Affiliations
- 1. Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS K53, Chamblee, GA, 30341-3717, USA
- 2. Rollins School of Public Health, Emory University, Atlanta, GA, USA
- 3. Division of Epidemiology and Surveillance, National Immunization Program, Atlanta, GA, USA