Breast Cancer Research and Treatment

, Volume 84, Issue 1, pp 49–60

Rho-Regulatory Proteins in Breast Cancer Cell Motility and Invasion

  • Min Lin
  • Kenneth L. van Golen

DOI: 10.1023/B:BREA.0000018424.43445.f3

Cite this article as:
Lin, M. & van Golen, K.L. Breast Cancer Res Treat (2004) 84: 49. doi:10.1023/B:BREA.0000018424.43445.f3


The importance of the Rho-GTPases in cancer progression, particularly in the area of metastasis, is becoming increasingly evident. This review will provide an overview of the role of the Rho-regulatory proteins in breast cancer metastatis.

GDP-dissociation inhibitors GTPase activating proteins guanine nucleotide exchange factors metastases Rho GTPases 

Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Min Lin
    • 1
  • Kenneth L. van Golen
    • 1
  1. 1.Department of Internal MedicineThe University of Michigan Comprehensive Cancer CenterAnn ArborUSA

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