Biomedical Microdevices

, Volume 6, Issue 3, pp 177–182

Microneedle Insertion Force Reduction Using Vibratory Actuation

  • Ming Yang
  • Jeffrey D. Zahn

DOI: 10.1023/B:BMMD.0000042046.07678.2e

Cite this article as:
Yang, M. & Zahn, J.D. Biomedical Microdevices (2004) 6: 177. doi:10.1023/B:BMMD.0000042046.07678.2e


The effect of vibratory actuation on microneedle insertion force was investigated. Hollow micro hypodermic injection needles were fabricated by a two-wafer polysilicon micromolding process. A vibratory actuator operating in the kHz range was coupled with the hypodermic microneedles. The force to insert microneedles into excized animal tissue was measured with a load cell. Results showed a greater than 70% reduction in microneedle insertion force by using vibratory actuation. The application of vibratory actuation provides a promising method to precisely control the microneedle insertion forces to overcome microneedle structural material limitations, minimize insertion pain, and enhance the efficiency of drug delivery.

microneedleinsertion forcevibratory actuationdrug delivery

Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Ming Yang
    • 1
  • Jeffrey D. Zahn
    • 2
  1. 1.Department of BioengineeringThe Pennsylvania State UniversityU.S.A
  2. 2.Department of BioengineeringThe Pennsylvania State University and Materials Research Institute, The Pennsylvania State UniversityU.S.A