Biomedical Microdevices

, Volume 6, Issue 3, pp 177-182

First online:

Microneedle Insertion Force Reduction Using Vibratory Actuation

  • Ming YangAffiliated withDepartment of Bioengineering, The Pennsylvania State University
  • , Jeffrey D. ZahnAffiliated withDepartment of Bioengineering, The Pennsylvania State University and Materials Research Institute, The Pennsylvania State University

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


The effect of vibratory actuation on microneedle insertion force was investigated. Hollow micro hypodermic injection needles were fabricated by a two-wafer polysilicon micromolding process. A vibratory actuator operating in the kHz range was coupled with the hypodermic microneedles. The force to insert microneedles into excized animal tissue was measured with a load cell. Results showed a greater than 70% reduction in microneedle insertion force by using vibratory actuation. The application of vibratory actuation provides a promising method to precisely control the microneedle insertion forces to overcome microneedle structural material limitations, minimize insertion pain, and enhance the efficiency of drug delivery.

microneedle insertion force vibratory actuation drug delivery