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Effect of Extracts from Rhodiola Rosea and Rhodiola Crenulata (Crassulaceae) Roots on ATP Content in Mitochondria of Skeletal Muscles

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Abstract

We studied the effects of oral treatment with extracts from Rhodiola rosea (50 mg/kg) and Rhodiola crenulata (50 mg/kg) roots on the duration of exhaustive swimming and ATP content in mitochondria of skeletal muscles in rats. Treatment with R. rosea extract significantly (by 24.6%) prolonged the duration of exhaustive swimming in comparison with control rats and rats treated with R. crenulata. R. rosea extract activated the synthesis or resynthesis of ATP in mitochondria and stimulated reparative energy processes after intense exercise. Experiments proved different pharmacological characteristics of R. rosea and R. crenulata: R. rosea is most effective for improving physical working capacity.

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Authors and Affiliations

  1. Russian Academy of Natural Sciences, Institute of Immunopathology, Moscow

    M. Abidov, F. Crendal, S. Grachev, R. Seifulla & T. Ziegenfuss

  2. I. M. Setchenov Medical Academy, Moscow

    M. Abidov, F. Crendal, S. Grachev, R. Seifulla & T. Ziegenfuss

  3. Russian Center for Higher Athletic Education, Moscow

    M. Abidov, F. Crendal, S. Grachev, R. Seifulla & T. Ziegenfuss

  4. Wordsworf Medical Center, Higher Institute of Human Health and Activities, USA

    M. Abidov, F. Crendal, S. Grachev, R. Seifulla & T. Ziegenfuss

Authors
  1. M. Abidov
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  2. F. Crendal
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  3. S. Grachev
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  4. R. Seifulla
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  5. T. Ziegenfuss
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Abidov, M., Crendal, F., Grachev, S. et al. Effect of Extracts from Rhodiola Rosea and Rhodiola Crenulata (Crassulaceae) Roots on ATP Content in Mitochondria of Skeletal Muscles. Bulletin of Experimental Biology and Medicine 136, 585–587 (2003). https://doi.org/10.1023/B:BEBM.0000020211.24779.15

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  • DOI: https://doi.org/10.1023/B:BEBM.0000020211.24779.15

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