Digestive Diseases and Sciences

, Volume 43, Issue 11, pp 2493–2499

Long-Term Consequences After Jejunoileal Bypass for Morbid Obesity

  • Michael P. Hocking
  • Gary L. Davis
  • Daisy A. Franzini
  • Edward R. Woodward
Article

DOI: 10.1023/A:1026698602714

Cite this article as:
Hocking, M.P., Davis, G.L., Franzini, D.A. et al. Dig Dis Sci (1998) 43: 2493. doi:10.1023/A:1026698602714

Abstract

This study assesses the long-term results ofjejunoileal bypass (JIB) in 43 prospectively followedpatients whose surgical bypass remained intact.Follow-up was 12.6 ± 0.25 years from JIB. Weightloss and improved lipid levels, glucose tolerance,cardiac function, and pulmonary function weremaintained. Adverse effects such as hypokalemia,cholelithiasis, and B12 or folate deficiency decreasedover time. The incidence of diarrhea remained constant(63% vs 64% at five years), while the occurrence ofhypomagnesemia increased (67% vs 43% at five years, P< 0.05). Nephrolithiasis occurred in 33% of patients. Hepatic fibrosis developed in 38% of patientsand was progressive. Overall, after more than 10 years,35% of patients appeared to benefit from JIB as definedby alleviation of preoperative symptoms and the development of only mild complications (vs47% at five years). On the other hand, irreversiblecomplications appeared to outweigh any benefit derivedfrom the JIB in 19% (vs no patients at five years; P < 0.01). In summary, patients with JIBremain at risk for complications, particularly hepaticfibrosis, even into the late postoperativeperiod.

OBESITY INTESTINAL BYPASS HEPATIC CIRRHOSIS 

Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • Michael P. Hocking
  • Gary L. Davis
  • Daisy A. Franzini
  • Edward R. Woodward

There are no affiliations available