Bulletin of Experimental Biology and Medicine

, Volume 136, Issue 2, pp 150–154

Role of Aqueous Medium in Mechanisms Underlying the Influence of Immunoactive Peptides in Ultralow Doses

Authors

    • Northwestern Division of the Russian Academy of Medical SciencesSt. Petersburg Institute of Bioregulation and Gerontology
  • V. Kh. Khavinson
    • Northwestern Division of the Russian Academy of Medical SciencesSt. Petersburg Institute of Bioregulation and Gerontology
  • V. V. Malinin
    • Northwestern Division of the Russian Academy of Medical SciencesSt. Petersburg Institute of Bioregulation and Gerontology
  • A. E. Grigor'ev
    • Northwestern Division of the Russian Academy of Medical SciencesSt. Petersburg Institute of Bioregulation and Gerontology
  • T. A. Kudryavtseva
    • Northwestern Division of the Russian Academy of Medical SciencesSt. Petersburg Institute of Bioregulation and Gerontology
Article

DOI: 10.1023/A:1026362706175

Cite this article as:
Grigor'ev, E.I., Khavinson, V.K., Malinin, V.V. et al. Bulletin of Experimental Biology and Medicine (2003) 136: 150. doi:10.1023/A:1026362706175
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Abstract

The mechanism underlying the influence of peptides in ultralow doses is based on distant signal transduction from the ligand molecules to target cells by means of water solitons. Biological activity of synthetic immunoactive peptides in concentrations below 10-18 M depends on their structural and conformational characteristics. The data on temperature dependencies of the near-infrared spectrum for solutions of these peptides are presented.

ultralow dosespeptidessignal transductionsolitonsinfrared spectroscopy

Copyright information

© Plenum Publishing Corporation 2003