Genetic Differentiation of the Population of Central Asia Inferred from Autosomal Markers
Purchase on Springer.com
$39.95 / €34.95 / £29.95*
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.
The gene pool of five ethnic groups of the Central Asian population was characterized using nine human-specific polymorphic insertion/deletion loci (ACE, PLAT, APOA1, PV92, F13B, A25, B65, CD4, Mt-Nuc). It has been shown for the first time that at the CD4 locus, the frequency of Alu(–) is inversely related to the Mongoloid component of the population. For the Central Asian populations, the lowest and highest frequencies of the Alu deletion at locus CD4 were recorded respectively in Dungans (0.04), immigrants from China, and Tajiks (0.15). The coefficient of gene differentiation in the Central Asian populations for all the genes was 2.8%, which indicates a relatively low level of population genetic subdivision in this region. The unity of the gene pool of the Central Asian Caucasoids was shown.
- Katsyuba, D.V. and Nikolaev, R.V., Etnografiya narodov Sibiri (Ethnography of Siberian Ethnic Groups), Kemerovo, 1994.
- Khit’ G.L., Race and Ethnogenetic Relationships in the Central Asian Population as Inferred from the Dermatoglyphic Data, in Problemy etnogeneza i etnicheskoi istorii narodov Srednei Azii i Kazakhstana (Problems of Ethnogenesis and Ethnic History of the Populations of Central Asian and Kazakhstan), Moscow, 1988, pp. 113–115.
- Gafurov, B.G., Tadzhiki. Drevneishaya, drevnyaya i srednevekovaya istoriya (Tajik: Ancient and Middle-Age History), Moscow: Nauka, 1972.
- Andriyanov, B.V., Ethnic History and Economic Cultural Development of Ancient and Middle-Age Ethnic Groups of Central Asia and Kazakhstan, in Problemy etnogeneza i etnicheskoi istorii narodov Srednei Azii i Kazakhstana (Problems of Ethnogenesis and Ethnic History of the Populations of Central Asian and Kazakhstan), Moscow, 1988, pp. 10–13.
- Alekseev, V.P., Geografiya chelovecheskikh ras (Geography of Human Races), Moscow: Nauka, 1974.
- Genofond i genogeografiya narodonaseleniya (The Gene Pool and Gene Geography of Human Populations), vol. 1, Genofond naseleniya Rossii i sopredel'nykh stran (The Gene Pool of the Populations of Russia and Adjacent Countries), St. Petersburg: Nauka, 2000.
- Stepanov, V.A., Khar'kov, V.N., Soltobaeva, Zh.O., et al., Y-Chromosomal Haplotypes in Populations of Central Asia, Genetika (Moscow), 2001, vol. 37, no. 2, pp. 256–259.
- Stepanov, V., Golubenko, M., Rootsi, S., et al., Diversity of Paternal and Maternal Lineages in Populations of Siberia and Central Asia, BDNE-WITA, 2001, Novosibirsk, 2001, p. 312.
- Novick, G.E., Novick, C.C., Yunis, J., et al., Polymorphic Alu Insertions and the Asian Origin of Native American Populations, Hum. Biol., 1998, vol. 70, pp. 23–39.
- Nasidze, Iv., Risch, G.M., Robichaux, M., et al., Alu Polymorphism and the Genetic Structure of Human Populations from the Caucasus, Eur. J. Hum. Genet., 2001, vol. 9, pp. 267–272.
- Majumder, P.P., Roy, B., Banrjee, S., et al., Human-Specific Insertion/Deletion Polymorphisms in Indian Populations and Their Possible Evolutionary Implications, Eur. J. Hum. Genet., 1999, vol. 7, pp. 435–446.
- Stepanov, V.A., Khitrinskaya, I.Yu., and Puzyrev, V.P., Genetic Differentiation of the Tuvinian Population by Polymorphic Alu Insertions, Genetika (Moscow), 2001, vol. 37, no. 4, pp. 563–569.
- Khitrinskaya, I.Yu., Stepanov, V.A., and Puzyrev, V.P., Analysis of the Polymorphism for Alu Insertions in Buryat Populations, Genetika (Moscow), 2001, vol. 37, no. 11, pp. 1553–1558.
- Stepanov, V.A., Puzyrev, V.P., Spiridonova, M.G., and Khitrinskaya, I.Yu., Analysis of the Polymorphism for Alu Insertions in the Urban and Rural Russian Populations of Siberia, Genetika (Moscow), 1999, vol. 35, no. 8, pp. 1138–1143.
- Tishkoff, S.A., Dietzsch, E., Speed, W., et al., Global Patterns of Linkage Equilibrium at the CD4 Locus and Modern Human Origins, Science, 1996, vol. 271, pp. 1380–1387.
- Batzer, M.A., Arcot, S.S., Phinney, J.M., et al., Genetic Variation of Recent Alu Insertions in Human Populations, J. Mol. Evol., 1996, vol. 42, pp. 22–29.
- Arcot, S.S., Fontius, J.J., Deininger, P.L., and Batzer, M.A., Identification and Analysis of a “Young” Polymorphic Alu Element, Biochim. Biophys. Acta, 1995, vol. 1263, pp. 99–102.
- Arcot, S.S., Wang, Z.W., Weber, J.L., et al., Alu Repeats: A Source for the Genesis of Primate Microsatellites, Genomics, 1995, vol. 29, pp. 136–144.
- Zhivotovsky, L.A., Populyatsionnaya biometriya (Population Biometrics), Moscow: Nauka, 1991.
- Nei, M., Molecular Evolutionary Genetics, New York: Columbia Univ. Press, 1987.
- Saitou, N. and Nei, M., The Neighbor-Joining Method: A New Method for Reconstructing Phylogenetic Trees, Mol. Biol. Evol., 1987, vol. 4, pp. 406–425.
- Felsenstein, J., PHYLIP, Version 3.5, Seattle: Univ. of Washington Press, 1993.
- Harpending, H.C. and Ward, R.H., Chemical Systematics and Human Populations, Biochemical Aspects of Evolutionary Biology Nitecki, M.H., Ed., Chicago: Univ. of Chicago Press, 1982, pp. 213–256.
- Stoneking, M., Fontius, J., Clifford, S.L., et al., Alu Insertion Polymorphism and Human Evolution: Evidence for a Larger Population Size in Africa, Genome Res., 1997, vol. 7, pp. 1061–1071.
- Wright, S., Isolation by Distance, Genetics, 1943, vol. 28, pp. 139–156.
- Wright, S., The Genetical Structure of Populations, Ann. Eugenics, 1951, vol. 15, pp. 323–354.
- Genetic Differentiation of the Population of Central Asia Inferred from Autosomal Markers
Russian Journal of Genetics
Volume 39, Issue 10 , pp 1175-1183
- Cover Date
- Print ISSN
- Online ISSN
- Kluwer Academic Publishers-Plenum Publishers
- Additional Links
- Author Affiliations
- 1. Research Institute of Medical Genetics, Tomsk Research Center, Russian Academy of Medical Sciences, Tomsk, 634050, Russia
- 2. Siberian Medical University, Tomsk, 634050, Russia
- 3. Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, 630090, Russia