European Journal of Epidemiology

, Volume 18, Issue 8, pp 763–768

Prenatal factors and use of anti-asthma medications in early childhood: A population-based Danish birth cohort study

  • Wei Yuan
  • Kirsten Fonager
  • Jørn Olsen
  • Henrik Toft Sørensen
Article

DOI: 10.1023/A:1025390420122

Cite this article as:
Yuan, W., Fonager, K., Olsen, J. et al. Eur J Epidemiol (2003) 18: 763. doi:10.1023/A:1025390420122

Abstract

To examine whether fetal growth indicators and other prenatal factors were associated with the use of anti-asthma medications during the first year of life, we conducted a follow-up study based on birth registry and prescription registry data of the county of North Jutland, Denmark. We identified 9705 singletons born between 1 April 1996 and 31 December 1997. They were followed to the end of the first year of life by linkage with a prescription registry. Prescription for asthma was defined as both a β-agonist and an inhaled glucocorticoid prescription. A prescription for asthma was presented to 3.8% of the infants during the first year of life. Maternal asthma, male gender, maternal smoking, multiparous births, young maternal age, and maternal non-cohabitation were associated with the risk of receiving a prescription for asthma. There were slightly increased trends in the risk with birth weight and placental weight. The increased risk was more pronounced in the groups of birth weight ≥3800 g (adjusted OR: 1.23, 95% CI: 0.88–1.73) and placental weight ≥750 g (adjusted OR: 1.44, 95% CI: 1.10–1.88). The increased risk was also associated with a high ponderal index of ≥2.7 g/cm3 (adjusted OR: 1.37, 95% CI: 1.06–1.76).

Asthma Fetal growth Infant Prenatal Risk factors 

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Wei Yuan
    • 1
    • 2
  • Kirsten Fonager
    • 3
  • Jørn Olsen
    • 1
  • Henrik Toft Sørensen
    • 1
    • 4
  1. 1.Danish Epidemiology Science CentreUniversity of AarhusAarhusDenmark
  2. 2.Shanghai Institute of Planned Parenthood ResearchShanghaiP.R. China
  3. 3.Department of Epidemiology and Social MedicineUniversity of AarhusAarhusDenmark
  4. 4.Department of Clinical EpidemiologyAarhus University Hospital and Aalborg HospitalAarhusDenmark

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