Virus Genes

, Volume 27, Issue 1, pp 103–110

Evolutionary History of Hepatitis B Virus Genotype F: An In-depth Analysis of Argentine Isolates

  • Flavia Guadalupe Piñeiro y Leone
  • Viviana Andrea Mbayed
  • Rodolfo Héctor Campos
Article

DOI: 10.1023/A:1025184704955

Cite this article as:
Piñeiro y Leone, F.G., Mbayed, V.A. & Campos, R.H. Virus Genes (2003) 27: 103. doi:10.1023/A:1025184704955

Abstract

A revised analysis on the evolutionary history of hepatitis B virus (HBV) genotype F is herein presented with the incorporation of two new complete genomes from Argentina. The study of the phylogenetic-tree topology, genetic distances, and amino acid mutations confirmed with high reliability the existence of four different genetic clusters of this genotype. Argentine isolates were located in two groups of viruses that showed a great inner homogeneity but, interestingly, divergence between them was in the order of that existing among groups from different locations. Although the origin of these two viral populations is not clear, they do not seem to derive from each other, therefore the existence of at least two founder viral populations in Argentina is a more acceptable explanation.

hepatitis B virus evolution genotype F 

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • Flavia Guadalupe Piñeiro y Leone
    • 1
  • Viviana Andrea Mbayed
    • 1
  • Rodolfo Héctor Campos
    • 1
  1. 1.Cátedra de Virología, Facultad de Farmacia y BioquímicaCiudad de Buenos AiresArgentina