Abstract
This report describes studies of the characteristics of serum albumin in rats with different predicted levels of resistance to emotional stress in control conditions and in conditions of experimental emotional stress. The effects of peptides increasing the resistance of animals to emotional stress (delta sleep-inducing peptide and Semax) on serum albumin were analyzed in rats predicted to be resistant and susceptible to emotional stress.
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REFERENCES
Yu. A. Gryzunov and G. E. Dobretsov (eds.), Serum Albumin in Clinical Medicine [in Russian], GÉOTAR. Moscow, Book 2 (1998).
Yu. A. Gryzunov, É. Yu. Misionzhnik, M. G. Uzbekov, and A. V. Molodetskikh, “The effects of haloperidol treatment on the dynamics of serum albumin binding in patients with schizophrenia, ” Klin. Lab. Diagnostika, 5, 31–33 (1994).
E. V. Koplik, Yu. A. Gryzunov, G. E. Dobretsov, and K. V. Sudakov, “Blood albumin in the mechanisms of emotional stress in rats, ” in: Humans and Treatment [in Russian], Moscow (2000), pp. 238–240.
E. V. Koplik, R. M. Salieva, and A. V. Korbunova, “The open field test as a prognostic criterion of resistance to emotional stress in Wistar rats, ” Zh. Vyssh. Nerv. Deyat., 45, 775–781 (1995).
E. V. Koplik, Yu. A. Gryzunov, L. V. Kopaeva, G. E. Dobretsov, and K. V. Sudakov, “Levels of non-esterified fatty acids in the serum albumin fraction in rats with different levels of movement activity in an open field test, ” Dokl. Akad. Nauk., 378, No. 1, 1–3 (2001).
Yu. M. Lopukhin, G. E. Dobretsov, and Yu. A. Gryzunov, “Conformational changes in the albumin molecule: a new type of response to a pathological process, ” Byull. Éksperim. Biol. Med., 130, No. 7, 4–8 (2000).
Yu. I. Miller and G. E. Dobretsov, “The molecular bases of a fluorescent method for assessing serum albumin binding capacity, ” Klin. Lab. Diagnostika, No. 5, 20–23 (1994).
É. Yu. Misionzhnik, T. V. Kovzhenko, Yu. A. Gryzunov, O. P. Vertogradova, and M. G. Uzbekov, Sotsial. Klin. Psikhiatr., 6, No. 2, 79–85 (1996).
K. V. Sudakov, “The antistress effects of delta sleep-inducing peptide, ” Fiziol. Zh. SSSR, 77, No. 3, 3–15 (1991).
K. V. Sudakov, Emotional Stress and Arterial Hypertension [in Russian], VNIIMI Press, Moscow (1976).
K. V. Sudakov, Systems Mechanisms of Emotional Stress [in Russian], Meditsina, Moscow (1981).
K. V. Sudakov, Individual Sensitivity to Emotional Stress [in Russian], Gorizont, Moscow (1998).
K. V. Sudakov, E. V. Koplik, R. M. Salieva, and Z. A. Kamenov, “Experimental emotional stress. Prognostic criteria for resistance and the role of oligopeptides, ” in: Emotional Stress. Physiological and Medico-Social Aspects [in Russian], Prapor, Khar'kov (1990), pp. 12–19.
V. N. Titov, “Albumin, saturated fatty acid transport, and metabolic stress syndrome, ” Klin. Lab. Diagnostika, No. 4, 3–11 (1999).
A. Ya. Kaplan, A. G. Kochetova, V. N. Nezavibathko, T. V. Rjasina, and I. P. Ashmarin, “Synthetic ACTH analogue Semax displays nootropic-like activity in humans, ” Neurosci. Res. Commun., 19, No. 2, 115–123 (1996).
K. V. Sudakov, J. P. Coghlan, A. B. Kotov, R. M. Salieva, Y. V. Polyntsev, and E. V. Koplik, “Delta sleep-inducing peptide sequelae in mechanisms of resistance to emotional stress, ” Ann. N.Y. Acad. Sci., 771, 240–251 (1995).
K. V. Sudakov, P. E. Umruhin, E. V. Koplik, and K. V. Anokhin, “Delta-sleep inducing peptide (DSIP) and ACTH(4-10) analogue influence fos-induction in the limbic structures of the rat brain under emotional stress, ” Stress, 00, 1–11 (in press).
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Koplik, E.V., Gryzunov, Y.A. & Dobretsov, G.E. Blood Albumin in the Mechanisms of Individual Resistance of Rats to Emotional Stress. Neurosci Behav Physiol 33, 827–832 (2003). https://doi.org/10.1023/A:1025109717945
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DOI: https://doi.org/10.1023/A:1025109717945