Journal of Biological Physics

, Volume 29, Issue 2, pp 117–121

Terahertz Time-Domain Spectroscopy of Glucose and Uric Acid

  • P.C. Upadhya
  • Y.C. Shen
  • A.G. Davies
  • E.H. Linfield
Article

DOI: 10.1023/A:1024476322147

Cite this article as:
Upadhya, P., Shen, Y., Davies, A. et al. Journal of Biological Physics (2003) 29: 117. doi:10.1023/A:1024476322147

Abstract

We report the use ofterahertz time-domain spectroscopy for thestudy of two therapeutic bio-molecules:glucose and uric acid. Terahertztransmission spectra of crystalline samplesof both molecules were measured between 0.1–3.0 THz using an evacuated spectroscopysystem. We propose that the stereo-isomersof glucose show spectral featuresoriginating from intermolecular vibrationalmodes, as do uric acid and its derivativemolecule, allantoin. In addition, wepresent a full temperature dependence ofthe terahertz absorption of L-glucose.

Glucoseintermoleculartemperature dependent absorptionterahertztime-domain spectroscopyuric acid

Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • P.C. Upadhya
    • 1
  • Y.C. Shen
    • 1
  • A.G. Davies
    • 2
  • E.H. Linfield
    • 1
  1. 1.Cavendish LaboratoryUniversity of CambridgeCambridgeUK
  2. 2.School of Electronic and Electrical EngineeringUniversity of LeedsLeedsUK