, Volume 118, Issue 2, pp 117-121

First online:

The Emergence of a Synthetic Theory of Intron Evolution

  • Sandro J. de SouzaAffiliated withLudwig Institute for Cancer Research, Sao Paulo Branch

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


The debate on the origin and evolution of the intron/exon structure of eukaryotic genes has witnessed profound changes in the last 10 years. Concepts from both the introns-early and introns-late theories have merged into a new synthetic theory of intron evolution. Here I review the debate and discuss the perspectives for the future.

intron evolution introns-early introns-late module