, Volume 118, Issue 2-3, pp 117-121

The Emergence of a Synthetic Theory of Intron Evolution

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Abstract

The debate on the origin and evolution of the intron/exon structure of eukaryotic genes has witnessed profound changes in the last 10 years. Concepts from both the introns-early and introns-late theories have merged into a new synthetic theory of intron evolution. Here I review the debate and discuss the perspectives for the future.