, Volume 79, Issue 3, pp 409-413

Polymorphisms in the Estrogen Receptor Beta Gene and Risk of Breast Cancer: No Association

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Abstract

Polymorphisms in the estrogen receptor beta (ERβ) gene may influence the cellular growth regulating effects of estradiol. In this first association study about breast cancer risk and polymorphisms in the ERβ gene we have screened 219 Finnish sporadic breast cancer cases and 248 ethnically matched male controls. No difference in the allele distribution of the six studied polymorphisms was found between the breast cancer and control groups.