Article

Neuroscience and Behavioral Physiology

, Volume 33, Issue 6, pp 607-611

First online:

The Effects of Ante- and Postnatal Hypoxia on the Central Nervous System and Their Correction with Peptide Hormones

  • M. V. MaslovaAffiliated withFaculty of Biology, M. V. Lomonosov Moscow State University
  • , A. S. MaklakovaAffiliated withFaculty of Biology, M. V. Lomonosov Moscow State University
  • , N. A. SokolovaAffiliated withFaculty of Biology, M. V. Lomonosov Moscow State University
  • , I. P. AshmarinAffiliated withFaculty of Biology, M. V. Lomonosov Moscow State University
  • , E. N. GoncharenkoAffiliated withFaculty of Biology, M. V. Lomonosov Moscow State University
  • , Ya. V. KrushinskayaAffiliated withFaculty of Biology, M. V. Lomonosov Moscow State University

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Abstract

Ante- and postnatal hypoxia significantly worsened the postnatal development of animals. The posthypoxic behavioral model included hyperactivity and decreased learning ability, these being typical manifestations of attention deficit disorder. A peptide constellation prevented and significantly improved posthypoxic postnatal development and eliminated the majority of negative behavioral changes.

ante- and postnatal hypoxia CNS peptidergic correction