The Histochemical Journal

, Volume 34, Issue 8, pp 369–381

Assembly, stability and integrity of basement membranes in vivo

  • Fabio Quondamatteo

DOI: 10.1023/A:1023675619251

Cite this article as:
Quondamatteo, F. Histochem J (2002) 34: 369. doi:10.1023/A:1023675619251


Basement membranes are layered structures of the extracellular matrix which separate cells of various kinds from the surrounding stroma. One of the frequently recurring questions about basement membranes is how these structures are formed in vivo. Up to a few years ago, it was thought that basement membranes were formed spontaneously by a process of self-assembly of their components. However, it has now become clear that cell membrane receptors for basement membrane components are essential factors for the formation and stability of basement membranes in vivo. The present review highlights the modern concepts of basement membrane formation.

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Fabio Quondamatteo
    • 1
  1. 1.Department of HistologyUniversity of GöttingenGöttingenGermany

Personalised recommendations