Digestive Diseases and Sciences

, Volume 48, Issue 3, pp 556–560

Hepatopulmonary Syndrome in Noncirrhotic Portal Hypertensive Patients

  • Sabahattin Kaymakoglu
  • Tevfik Kahraman
  • Hasan Kudat
  • Kadir Demir
  • Yilmaz Cakaloglu
  • Isik Adalet
  • Dinc Dincer
  • Fatih Besisik
  • Güngör Boztas
  • Ahmet Bilge Sözen
  • Zeynel Mungan
  • Atilla Okten
Article

DOI: 10.1023/A:1022549018807

Cite this article as:
Kaymakoglu, S., Kahraman, T., Kudat, H. et al. Dig Dis Sci (2003) 48: 556. doi:10.1023/A:1022549018807

Abstract

Hepatopulmonary syndrome has yet not been sufficiently assessed in noncirrhotic portal hypertension. The prevalence of hepatopulmonary syndrome was determined in 31 consecutive patients with noncirrhotic portal hypertension (19 idiopathic portal hypertension, 7 portal vein thrombosis, 5 congenital hepatic fibrosis) and 46 patients with liver cirrhosis. Contrast echocardiography was carried out in all patients. Macroaggregated albumin lung perfusion scans were performed in patients with positive contrast echocardiogram. Hepatopulmonary syndrome was detected in 5 (10.8%) cirrhotic and 3 (9.7%) noncirrhotic portal hypertensive patients (2 idiopathic portal hypertension, 1 portal vein thrombosis). All patients with hepatopulmonary syndrome had an increased shunt fraction (13–62%) and a decreased diffusion capacity of carbon monoxide (40–79%), and 7 of them were hypoxemic (PaO2, 31.6–69.8 mm Hg). These findings show that hepatopulmonary syndrome may occur in both liver cirrhosis and noncirrhotic portal hypertension and that portal hypertension is the predominant etiopathogenic factor related to hepatopulmonary syndrome.

hepatopulmonary syndrome liver cirrhosis noncirrhotic portal hypertension 

Copyright information

© Plenum Publishing Corporation 2003

Authors and Affiliations

  • Sabahattin Kaymakoglu
  • Tevfik Kahraman
  • Hasan Kudat
  • Kadir Demir
  • Yilmaz Cakaloglu
  • Isik Adalet
  • Dinc Dincer
  • Fatih Besisik
  • Güngör Boztas
  • Ahmet Bilge Sözen
  • Zeynel Mungan
  • Atilla Okten

There are no affiliations available

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