Oldendorf, W. H. 1971. Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. Am. J. Physiol. 221:1629–1639.
Brightman, M. W. 1977. Morphology of blood-brain interfaces. Exp. Eye Res. 25(Suppl.):1–25.
Pardridge, W. M. 1977. Regulation of amino acid availability to the brain. Pages 141–204, in Wurtman, R. J., and Wurtman, J. J., (eds.), Nutrition and the Brain, Raven Press, New York.
Pardridge, W. M., and Oldendorf, W. H. 1977. Transport of metabolic substrates through the blood-brain barrier. J. Neurochem. 28:5–12.
Pardridge, W. M. 1983. Brain metabolism: A perspective from the blood-brain barrier. Physiol. Rev. 63:1481–1535.
Smith, Q. R., and Stoll, J. 1998, in press. Blood-brain barrier amino acid transport. in Pardridge, W. M. (ed.), An Introduction to the Blood-Brain Barrier: Methodology and Biology, Cambridge University Press.
Oldendorf, W. H., Sisson, W. B., and Silverstein, A. 1971. Brain uptake of selenomethionine Se75. II. Reduced brain uptake of selenomethionine Se75 in phenylketonuria. Arch Neurol. 24:524.
Pardridge, W. M., and Oldendorf, W. H. 1975. Kinetic analysis of blood-brain barrier transport of amino acids. Biochim. Biophys. Acta. 401:128–136.
Drewes, L. R. 1998. Biology of the blood-brain glucose transporter. in Pardridge, W. M. (ed.), An Introduction to the Blood-Brain Barrier: Methodology and Biology, Cambridge University Press, in press.
Malandro, M. S., and Kilberg, M. S. 1996. Molecular biology of mammalian amino acid transporters. Annu. Rev. Biochem. 65:305–36.
Oldendorf, W. H. 1970. Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard. Brain Res. 24:372.
Pardridge, W. M., and Oldendorf, W. H. 1975. Kinetics of blood-brain barrier transport of hexoses. Biochim. Biophys. Acta. 382:377–392.
Pardridge, W. M. 1977. Kinetics of competitive inhibition of neutral amino acid transport across the blood-brain barrier. J. Neurochem. 28:103–108.
Pardridge, W. M., and Mietus, L. J. 1982. Kinetics of neutral amino acid transport through the blood-brain barrier of the newborn rabbit. J. Neurochem. 38:955–962.
Miller, L. P., Pardridge, W. M., Braun, L. D., and Oldendorf, W. H. 1985. Kinetic constants for blood-brain barrier amino acid transport in conscious rats. J. Neurochem. 45:1427–1432.
Pardridge, W. M., and Fierer, G. 1985. Blood-brain barrier transport of butanol and water relative to N-isopropyl-p-[125I] iodoamphetamine (IMP) as the internal reference. J. Cereb. Blood Flow Metab. 5:275–281.
Pardridge, W. M., Landaw, E. M., Miller, L. P., Braun, L. D., and Oldendorf, W. H. 1985. Carotid artery injection technique: Bounds for bolus mixing by plasma and by brain. J. Cereb. Blood Flow Metab. 5:576–583.
Choi, T., and Pardridge, W. M. 1986. Phenylalanine transport at the human blood-brain barrier. Studies in isolated human brain capillaries. J. Biol. Chem. 261:6536–6541.
Hargreaves, K. M., and Pardridge, W. M. 1988. Neutral amino acid transport at the human blood-brain barrier. J. Biol. Chem. 263:19392–19397.
Smith, Q. R., Aoyagi, M., Robinson, P. J., and Rapoport, S. I. 1987. Kinetics of neutral amino acid transport across the blood-brain barrier. J. Neurochem. 49:1651–1658.
Christensen, H. N. 1969. Some special kinetic problems of transport. Adv. Enzymol. 32:1–20.
Fernstrom, J. D., and Wurtman, R. J. 1972. Brain serotonin content-physiological regulation by plasma neutral amino acids. Science. 178:414–416.
Munro, H. N., Fernstrom, J. D., and Wurtman, R. J. 1975. Insulin, plasma aminoaid imbalance, and hepatic coma. Lancet. 1:722–726.
Pardridge, W. M. 1975. Tryptophan and hepatic encephalopathy. The Lancet. 1:1035.
James, J. H., Escourrou, J., and Fischer, J. E. 1978. Blood-brain neutral amino acid transport activity is increased after portacaval anastomosis. Science. 200:1395–1397.
Carter, D. C., and He, J. X. 1994. Structure of serum albumin. Adv. Protein Chem. 45:153–203.
Brown, J. R. 1977. Serum albumin: Amino acid sequence. Pages 27–51, in Rosehoer, V. M., Oratz, M., and Rothschild, M. A. (eds.), Albumin Structure, Function, and Uses, Pergamon Press, New York.
Wilting, J., Kremer, J. M. H., Ijzerman, A. P., and Schulman, G. 1982. The kinetics of the binding of warfarin to human serum albumin as studied by stopped-flow spectrophotometry. Biochim. Biophys. Acta. 706:96–104.
Reed, R. G., and Burrington, C. M. 1989. The albumin receptor effect may be due to a surface-induced conformational change in albumin. J. Biol. Chem. 264:9867–9872.
Pardridge, W. M. 1998, in press. Targeted delivery of hormones to tissues by plasma proteins. In Conn, P. M. (ed.), Handbook of Physiology—Cellular Mechanisms, Oxford University Press, New York.
Pardridge, W. M., and Fierer, G. 1990. Transport of tryptophan into brain from the circulating albumin-bound pool in rats and in rabbits. J. Neurochem. 54:971–976.
Binek-Singer, P., and Johnson, T. C. 1982. The effects of chronic hyperphenylalaninemia on mouse brain protein synthesis can be prevented by other amino acids. Biochem. J. 206:407–414.
Hargreaves-Wall, K. M., Buciak, J. B., and Pardridge, W. M. 1990. Measurement of free-intracellular and transfer RNA amino acid specific activity and protein synthesis in rat brain in vivo. J. Cerebral Blood Flow Metabol. 10:162–169.
Wall, K. M., and Pardridge, W. M. 1990. Decreases in brain protein synthesis elicited by moderate increases in plasma phenylalanine. Biochem. Biophys. Res. Comm. 168:1177–1183.
Smith, C. B., Deibler, G. E., Eng, N., Schmidt, K., and Sokoloff, L. 1988. Measurement of local cerebral protein synthesis in vivo: Influence of recycling of amino acids derived from protein degradation. Proc. Natl. Acad. Sci. USA 85:9341–9345.
Hawkins, R. A., Mans, A. M., and Biebuyck, J. F. 1987. Changes in brain metabolism in hepatic encephalopathy. Neurochem. Pathol. 6:35–66.
Filer, L. J. Jr., and Stegink, L. D. 1987. Effect of aspartame on plasma phenylalanine concentration in humans. Pages 25–56, in Wurtman, R. J. and Ritter-Walker E. (eds.), Dietary Phenylalanine and Brain Function, Center for Brain Sciences and Metabolism Charitable Trust, Mass.
Levy, H. L., and Waisbren, S. E. 1983. Effects of untreated maternal phenylketonuria and hyperphenylalaninemia on the fetus. N. Engl. J. Med., 309:1269–1274.
Pardridge, W. M. 1986. Potential effects of the dipeptide sweetener aspartame on the brain. Pages 199–241, in Wurtman, R. J., and Wurtman, J. J. (eds.), Nutrition and the Brain, Vol. 7, Raven Press, New York.
Kirkman, H. N. Jr., and Hicks, R. E. 1984. More on untreated maternal hyperphenylalaninemia. N. Engl. J. Med. 311:1125.
Krause, W., Halminski, M., McDonald, L., Dembure, P., Salvo, R., Freides, D., and Elsas, L. 1985. Biochemical and neuropsychological effects of elevated plasma phenylalanine in patients with treated phenylketonuria. J. Clin. Invest. 75:40–48.
Pardridge, W. M. 1987. Phenylalanine transport at the human blood-brain barrier. Pages 43–64, in Kaufman, S. (ed.), Amino Acids in Health and Disease: New Perspectives, Alan R. Liss, Inc., New York.