Journal of Nanoparticle Research

, Volume 4, Issue 4, pp 313–317

Selfassembly of Metallic Nanoparticle Arrays by DNA Scaffolding

  • Shoujun Xiao
  • Furong Liu
  • Abbey E. Rosen
  • James F. Hainfeld
  • Nadrian C. Seeman
  • Karin Musier-Forsyth
  • Richard A. Kiehl
Article

DOI: 10.1023/A:1021145208328

Cite this article as:
Xiao, S., Liu, F., Rosen, A.E. et al. Journal of Nanoparticle Research (2002) 4: 313. doi:10.1023/A:1021145208328

Abstract

We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaffolding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.

nanoparticlesDNAnanotechnologyself-assemblynanoelectronics

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Shoujun Xiao
    • 1
    • 2
  • Furong Liu
    • 2
  • Abbey E. Rosen
    • 2
  • James F. Hainfeld
    • 3
  • Nadrian C. Seeman
    • 2
  • Karin Musier-Forsyth
    • 2
  • Richard A. Kiehl
    • 4
  1. 1.Electrical and Computer Engineering DepartmentUniversity of MinnesotaMinneapolisUSA
  2. 2.Chemistry DepartmentUniversity of MinnesotaMinneapolisUSA
  3. 3.Biology DepartmentBrookhaven National LaboratoryUptonUSA
  4. 4.Electrical and Computer Engineering DepartmentUniversity of MinnesotaMinneapolisUSA