Selfassembly of Metallic Nanoparticle Arrays by DNA Scaffolding
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We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaffolding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.
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- Selfassembly of Metallic Nanoparticle Arrays by DNA Scaffolding
Journal of Nanoparticle Research
Volume 4, Issue 4 , pp 313-317
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- Kluwer Academic Publishers
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- 1. Electrical and Computer Engineering Department, University of Minnesota, Minneapolis, MN, 55455, USA
- 2. Chemistry Department, University of Minnesota, Minneapolis, MN, 55455, USA
- 3. Biology Department, Brookhaven National Laboratory, Upton, NY, 11973, USA
- 4. Electrical and Computer Engineering Department, University of Minnesota, Minneapolis, MN, 55455, USA