Ivanikov, I.O., Brekhova, M.E., Samonina, G.E. et al. Bulletin of Experimental Biology and Medicine (2002) 134: 73. doi:10.1023/A:1020621124776
Experiments used is combination with traditional preparations (omeprasole, de-nol, and solcoseril), Semax peptide (Met-Glu-His-Phe-Pro-Gly-Pro) possessing nootropic and neuroprotective activity significantly promoted ulcer healing in patients with refractory peptic ulcers. On day 14 of treatment ulcer healing was observed in 89.5% patients receiving intranasal Semax (1% solution, 2-4 drops 3 times a day for 10 days) vs. 30.8% in the control group. Clinical studies of antiulcer activity of Semax in different combinations with usual antiulcer drugs are needed.
Semax peptic ulcer cicatrization period clinical study