Journal of Assisted Reproduction and Genetics

, Volume 19, Issue 9, pp 433–437

Preimplantation Genetic Diagnosis for Elective Sex Selection, the IVF Market Economy, and the Child—Another Long Day's Journey into Night?

  • E.Scott Sills
  • Gianpiero D. Palermo
Article

DOI: 10.1023/A:1016819908612

Cite this article as:
Sills, E. & Palermo, G.D. J Assist Reprod Genet (2002) 19: 433. doi:10.1023/A:1016819908612

Abstract

The promise of medical innovation has long evoked social commentary, particularly when personal reproductive autonomy may be involved. Development of the oral contraceptive, effective and safe surgical sterilization, and later IVF and ICSI are among the revolutionary developments where the initial reactions were dubious but were accorded mainstream status with sufficient clinical experience. In each instance, debate about the moral and social implications of these treatments accompanied their introduction into the medical marketplace. This pattern appears to be repeating itself in connection with the use of preimplantation genetic diagnosis (PGD) for elective sex selection of human embryos. As with prior challenges in reproductive medicine, the development of meaningful “guidelines” for this latest controversy has proven to be a contentious task. Indeed, the progression of ethics committee reports from the Society for Reproductive Medicine seems to echo the ambivalence within society at large regarding this issue. In this report, we chronicle sex selection claims based on sperm sorting, and describe how flow cytometry and especially PGD have facilitated this selection at the gamete and embryo stage, respectively. In doing so, we also explore market forces and practitioner considerations associated with the application of PGD for this; related ethical issues with particular emphasis on the progeny derived from such treatment are also.

EthicsIVFPGDsex selection

Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • E.Scott Sills
    • 1
  • Gianpiero D. Palermo
    • 2
  1. 1.Georgia Reproductive Specialists LLCAtlanta
  2. 2.Department of Obstetrics and Gynecology, Center For Reproductive Medicine and InfertilityWeill Medical College of University, The New York – Presbyterian HospitalNew York