Pharmaceutical Research

, Volume 3, Issue 6, pp 318–326

lontophoretic Devices for Drug Delivery

  • Praveen Tyle

DOI: 10.1023/A:1016327822325

Cite this article as:
Tyle, P. Pharm Res (1986) 3: 318. doi:10.1023/A:1016327822325


Transdermal drug delivery of ionized drugs can be enhanced by iontophoresis. Drug in the ionic form, contained in some reservoir, can be “phoresed” through the skin with a small current across two electrodes, one above the reservoir and one at a distal skin location. Positive ions can be introduced from the positive pole, or negative ions from the negative pole. The design and development of iontophoretic devices are rather simple. Some of the principles of operation and the advantages/disadvantages and clinical implications associated with these devices are outlined in this review.

IontophoresisDrug Delivery DevicesControlled Drug DeliveryTransdermal Drug DeliveryElectroosmosisDrug DeliveryDevices

Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Praveen Tyle
    • 1
  1. 1.American Cyanamid CompanyPrinceton