M. Yamazaki, H. Suzuki, and Y. Sugiyama. Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics. Pharm. Res.
O. Takenaka, T. Hori, H. Suzuki, and Y. Sugiyama. Carrier-mediated active transport of the glucuronide and sulfate of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into rat liver: quantitative comparison of permeability in isolated hepatocytes, perfused liver and liver in vivo. J. Pharmacol. Exp. Ther.
M. Ishigami, T. Tokui, T. Komai, K. Tsukahara, M. Yamazaki, and Y. Sugiyama. Evaluation of the uptake of pravastatin by perfused rat liver and primary cultured rat hepatocytes. Pharm. Res.
E. Jacquemin, B. Hagenbuch, B. Stieger, A. W. Wolkoff, and P. J. Meier. Expression cloning of a rat liver Na+-independent organic anion transporter. Proc. Natl. Acad. Sci. USA
B. Noé, B. Hagenbuch, B. Stieger, and P. J. Meier. Isolation of multispecific organic anion and cardiac glycoside transporter from rat brain. Proc. Natl. Acad. Sci. USA
V. Cattori, B. Hagenbuch, N. Hagenbuch, B. Stieger, R. Ha, K. E. Winterhalter, and P. J. Meier. Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver. FEBS Lett
M. Kakyo, M. Unno, T. Tokui, R. Nakagomi, T. Nishio, H. Iwasaki, D. Nakai, M. Sei, M. Suzuki, T. Naitoh, S. Matsuno, H. Yawo, and T. Abe. Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1. Gastroenterology
T. Sekine, S. H. Cha, M. Tsuda, N. Apiwattanakul, N. Nakajima, Y. Kanai, and H. Endou. Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 429:179–182 (1998).
H. Kusuhara, T. Sekine, N. Utsunomiya-Tate, M. Tsuda, R. Kojima, S. H. Cha, Y. Sugiyama, Y. Kanai, and H. Endou. Molecular cloning and characterization of a new multiple organic anion transporter from rat brain. J. Biol. Chem.
H. Ishizuka, K. Konno, H. Naganuma, K. Nishimura, H. Kouzuki, H. Suzuki, B. Stieger, P. J. Meier, and Y. Sugiyama. Transport of temocaprilat into rat hepatocytes: role of organic anion transporting polypeptides. J. Pharmacol. Exp. Ther.
B. Hsiang, Y. Zhu, Z. Wang, Y. Wu, V. Sasseville, W-P Yang, and T. G. Kirchgessner. A novel human hepatic organic anion transporting polypeptide (OATP2). J. Biol. Chem.
N. Kanai, R. Lu, A. W. Wolkoff, and V. L. Schuster. Transient expression of oatp organic anion transporter in mammalian cells: identification of candidate substrates. Am. J. Physiol.
U. Eckhardt, A. Schroeder, B. Stieger, M. Höchli, L. Landmann, R. Tynes, P. J. Meier, and B. Hagenbuch. Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells. Am. J. Physiol.
N. Kanai, R. Lu, Y. Bao, A. W. Wolkoff, M. Vore, and V. L. Schuster. Estradiol 17?-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am. J. Physiol.
J. E. van Montfoort, B. Hagenbuch, K. E. Fattinger, M. Müller, G. M. M. Groothuis, D. K. F. Meijer, and P. J. Meier. Polyspecific organic anion transporting polypeptides mediate hepatic uptake of amphipathic type II organic cations. J. Pharmacol. Exp. Ther.
T. Abe, M. Kakyo, H. Sakagami, T. Tokui, T. Nishio, M. Tanemoto, H. Nomura, S. C. Hebert, S. Matsuno, H. Kondo, and H. Yawo. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. J. Biol. Chem.
C. Reichel, J. E. van Montfort, V. Cattori, C. Rahner, B. Stieger, T. Kamisako, and P. J. Meier. Localization and function of the organic anion-transporting polypeptide oatp2 in rat liver. Gastroenterology
L. Li, P. J. Meier, and N. Ballatori. Oatp2 mediated bidirectional organic solute transport: a role for intracellular glutathione. Mol. Phamacol. 58:335–340 (2000).
R. J. Bertz and G. R. Granneman. Use of in vitro and in vivo data to estimation the likelihood of metabolic pharmacokinetic interactions. Clin. Pharmacokinet.
H. Kouzuki, H. Suzuki, K. Ito, R. Ohashi, and Y. Sugiyama. Contribution of organic anion transporting polypeptide to uptake of its possible substrates into rat hepatocytes. J. Pharmacol. Exp. Ther.
H. Niwa, K. Yamamura, and J. Miyazaki. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene
A. Schroeder, U. Eckhardt, B. Stieger, R. Tynes, C. D. Schteingart, A. F. Hofmann, P. J. Meier, and B. Hagenbuch. Substrate specificity of the rat liver Na+-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells. Am. J. Physiol.
O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem.
K. Yamaoka, Y. Tanigawara, Y. Nakagami, and T. Uno. A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio-Dyn.
H. Kouzuki, H. Suzuki, and Y. Sugiyama. Pharmacokinetic study of the hepatobiliary transport of indomethacin. Pharm. Res.
H. Kouzuki, H. Suzuki, B. Stieger, P. J. Meier, and Y. Sugiyama. Characterization of the transport properties of organic anion transporting polypeptide 1 (oatp1) and Na+/taurocholate cotransporting polypeptide (Ntcp): comparative studies on the inhibitory effect of their possible substrates in hepatocytes and cDNA-transfected COS-7 cells. J. Pharmacol. Exp. Ther.
K. Fattinger, V. Cattori, B. Hagenbuch, P. J. Meier, and B. Stieger. Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2. Hepatology
A. Hedman and D. K. F. Meijer. Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes. J. Pharm. Sci.
B. Hagenbuch, B. F. Scharschmidt, and P. J. Meier. Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes. Biochem. J.
H. Kouzuki, H. Suzuki, K. Ito, R. Ohashi, and Y. Sugiyama. Contribution of sodium taurocholate co-transporting polypeptide to the uptake of its possible substrates into rat hepatocytes. J. Pharmacol. Exp. Ther.