Biotechnology Letters

, Volume 23, Issue 23, pp 1953–1956

Large-scale separation of magnetic bioaffinity adsorbents

  • Ivo Šafařík
  • Lucie Ptáčková
  • Mirka Šafaříková
Article

DOI: 10.1023/A:1013742002533

Cite this article as:
Šafařík, I., Ptáčková, L. & Šafaříková, M. Biotechnology Letters (2001) 23: 1953. doi:10.1023/A:1013742002533

Abstract

Flat magnetic separator was used to separate magnetic bioaffinity adsorbents from litre volumes of suspensions. Both magnetic cross-linked erythrocytes and magnetic chitosan were efficiently separated; at least 95% adsorbent recovery was achieved at maximum flow rate (1680 ml min−1). Using this system low amounts of trypsin were concentrated from large sample volumes using magnetic erythrocytes as affinity adsorbent.

flat magnetic separatormagnetic adsorbentsmagnetic separation

Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Ivo Šafařík
    • 1
  • Lucie Ptáčková
    • 1
  • Mirka Šafaříková
    • 1
  1. 1.Laboratory of Biochemistry and Microbiology, Institute of Landscape EcologyČeské BudějoviceCzech Republic